Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090342021> ?p ?o ?g. }
- W2090342021 endingPage "287" @default.
- W2090342021 startingPage "283" @default.
- W2090342021 abstract "CNS axons display a poor regenerative response to injury. In multiple sclerosis (MS), failure of damaged axons to regenerate may be a major factor underlying non-reversible neurologic dysfunction. Nogo is a development-related molecule inhibiting axonal regeneration and is a major component of CNS myelin.CSF from 114 patients with remitting relapsing MS (RR-MS) and secondary progressive MS (SP-MS) and 153 controls, as well as CNS tissue from 3 patients with MS and 2 controls, were used for this study.We found soluble 20 kDa Nogo-A product in 96% (110/114) of CSF samples from patients with MS compared with 0/18 from meningo-encephalomyelitis, 0/125 from control subjects with other neurologic diseases, and 0/10 from CNS autoimmune diseases. Nogo-A products were present both in RR-MS and SP-MS, as well as in early cases of the disease, but not in neuromyelitis optica. The same Nogo A product was detected in CNS tissue from all patients with MS but not in control CNS tissue.Soluble Nogo-A may be specific for the CSF of patients with multiple sclerosis and its presence may predict failure of axonal regeneration within the CNS." @default.
- W2090342021 created "2016-06-24" @default.
- W2090342021 creator A5034380106 @default.
- W2090342021 creator A5047145747 @default.
- W2090342021 creator A5057467113 @default.
- W2090342021 creator A5063539967 @default.
- W2090342021 date "2007-01-22" @default.
- W2090342021 modified "2023-09-30" @default.
- W2090342021 title "Soluble Nogo-A, an inhibitor of axonal regeneration, as a biomarker for multiple sclerosis" @default.
- W2090342021 cites W1500809101 @default.
- W2090342021 cites W1501424430 @default.
- W2090342021 cites W1529553680 @default.
- W2090342021 cites W1536256102 @default.
- W2090342021 cites W1582674063 @default.
- W2090342021 cites W1585651720 @default.
- W2090342021 cites W1676176718 @default.
- W2090342021 cites W1952053031 @default.
- W2090342021 cites W1986173197 @default.
- W2090342021 cites W1990837582 @default.
- W2090342021 cites W2025778924 @default.
- W2090342021 cites W2032304318 @default.
- W2090342021 cites W2034163178 @default.
- W2090342021 cites W2034260461 @default.
- W2090342021 cites W2035763636 @default.
- W2090342021 cites W2037503683 @default.
- W2090342021 cites W2038350243 @default.
- W2090342021 cites W2040051757 @default.
- W2090342021 cites W2057969974 @default.
- W2090342021 cites W2065200510 @default.
- W2090342021 cites W2065835947 @default.
- W2090342021 cites W2071993046 @default.
- W2090342021 cites W2074074558 @default.
- W2090342021 cites W2105490558 @default.
- W2090342021 cites W2110422864 @default.
- W2090342021 cites W2122894564 @default.
- W2090342021 cites W2135247160 @default.
- W2090342021 doi "https://doi.org/10.1212/01.wnl.0000252357.30287.1d" @default.
- W2090342021 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17242333" @default.
- W2090342021 hasPublicationYear "2007" @default.
- W2090342021 type Work @default.
- W2090342021 sameAs 2090342021 @default.
- W2090342021 citedByCount "52" @default.
- W2090342021 countsByYear W20903420212012 @default.
- W2090342021 countsByYear W20903420212013 @default.
- W2090342021 countsByYear W20903420212014 @default.
- W2090342021 countsByYear W20903420212015 @default.
- W2090342021 countsByYear W20903420212016 @default.
- W2090342021 countsByYear W20903420212017 @default.
- W2090342021 countsByYear W20903420212018 @default.
- W2090342021 countsByYear W20903420212021 @default.
- W2090342021 countsByYear W20903420212022 @default.
- W2090342021 crossrefType "journal-article" @default.
- W2090342021 hasAuthorship W2090342021A5034380106 @default.
- W2090342021 hasAuthorship W2090342021A5047145747 @default.
- W2090342021 hasAuthorship W2090342021A5057467113 @default.
- W2090342021 hasAuthorship W2090342021A5063539967 @default.
- W2090342021 hasConcept C126322002 @default.
- W2090342021 hasConcept C142724271 @default.
- W2090342021 hasConcept C171056886 @default.
- W2090342021 hasConcept C203014093 @default.
- W2090342021 hasConcept C2777899865 @default.
- W2090342021 hasConcept C2778486448 @default.
- W2090342021 hasConcept C2778609137 @default.
- W2090342021 hasConcept C2780640218 @default.
- W2090342021 hasConcept C2781137167 @default.
- W2090342021 hasConcept C2781197716 @default.
- W2090342021 hasConcept C2908708501 @default.
- W2090342021 hasConcept C529278444 @default.
- W2090342021 hasConcept C55493867 @default.
- W2090342021 hasConcept C71924100 @default.
- W2090342021 hasConcept C86803240 @default.
- W2090342021 hasConcept C95444343 @default.
- W2090342021 hasConceptScore W2090342021C126322002 @default.
- W2090342021 hasConceptScore W2090342021C142724271 @default.
- W2090342021 hasConceptScore W2090342021C171056886 @default.
- W2090342021 hasConceptScore W2090342021C203014093 @default.
- W2090342021 hasConceptScore W2090342021C2777899865 @default.
- W2090342021 hasConceptScore W2090342021C2778486448 @default.
- W2090342021 hasConceptScore W2090342021C2778609137 @default.
- W2090342021 hasConceptScore W2090342021C2780640218 @default.
- W2090342021 hasConceptScore W2090342021C2781137167 @default.
- W2090342021 hasConceptScore W2090342021C2781197716 @default.
- W2090342021 hasConceptScore W2090342021C2908708501 @default.
- W2090342021 hasConceptScore W2090342021C529278444 @default.
- W2090342021 hasConceptScore W2090342021C55493867 @default.
- W2090342021 hasConceptScore W2090342021C71924100 @default.
- W2090342021 hasConceptScore W2090342021C86803240 @default.
- W2090342021 hasConceptScore W2090342021C95444343 @default.
- W2090342021 hasIssue "4" @default.
- W2090342021 hasLocation W20903420211 @default.
- W2090342021 hasLocation W20903420212 @default.
- W2090342021 hasOpenAccess W2090342021 @default.
- W2090342021 hasPrimaryLocation W20903420211 @default.
- W2090342021 hasRelatedWork W1789772972 @default.
- W2090342021 hasRelatedWork W2017885089 @default.
- W2090342021 hasRelatedWork W2057576992 @default.
- W2090342021 hasRelatedWork W2090342021 @default.
- W2090342021 hasRelatedWork W2322830492 @default.