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• W2090392812 abstract "Recent studies have suggested that heart-type fatty acid-binding protein (H-FABP) may detect ongoing myocardial damage involved in the progression of acute coronary syndromes (ACS). This study was prospectively designed to examine whether the combination of H-FABP, a marker for ongoing myocardial damage, and ischemia-modified albumin (IMA), a marker for myocardial ischemia, would effectively diagnose patients with ACS. H-FABP values above 1.5 µg/l can be correctly measured via an ELISA and 6 µg/l is the currently used cut-off value (1–3). We measured serum H-FABP and IMA of 108 patients on admission within 12 hr after onset of chestpain and normal troponin T. serum samplesfrom ACS group (n=82) had decreased capacity of ACB [64 (61–67) U/ml] compared with non-ACS ischemic chest pain group (n=26) samples [75 (71–78) U/ml] (P<0.05). The combination of IMA and H-FABP usually had better sensitivity [96.3% (92.2–100%)] (P<0.05) and accuracy [92.6 (87.7–97.5%)] (P<0.05) than when individually used. Thus, the combination of H-FABP and IMA measurements after initiation of chest pain may be highly effective for risk stratification in patients with ACS and normal cardiac troponin T. J. Clin. Lab. Anal. 23:14–18, 2009. © 2009 Wiley-Liss, Inc." @default.
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• W2090392812 date "2009-01-01" @default.
• W2090392812 modified "2023-09-28" @default.
• W2090392812 title "Prognostic value of combination of heart-type fatty acid-binding protein and ischemia-modified albumin in patients with acute coronary syndromes and normal troponin T values" @default.
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• W2090392812 doi "https://doi.org/10.1002/jcla.20276" @default.
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