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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090413012> ?p ?o ?g. }

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• W2090413012 abstract "Intrathecal injection of 0.25 μg of undecapeptide substance P antagonist (SPA) produced transient antinociception with a peak effect at 5 min. Increasing the SPA dose resulted in neurotoxicity. Intrathecal injection of the opioid peptide biphalin (BIP) produced antinociception for over 3 hrs without neurotoxicity. Co-administration of SPA (at subtoxic doses) increased BIP's antinociceptive effect. Naltrexone reversed analgesia due to BIP alone as well as after BIP+SPA." @default.
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• W2090413012 date "1994-01-01" @default.
• W2090413012 modified "2023-10-16" @default.
• W2090413012 title "Spinal co-administration of peptide substance P antagonist increases antinociceptive effect of the opioid peptide biphalin" @default.
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• W2090413012 doi "https://doi.org/10.1016/0024-3205(94)00494-3" @default.
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