Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090417259> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2090417259 endingPage "E5" @default.
- W2090417259 startingPage "E5" @default.
- W2090417259 abstract "It is likely that brain tissue acidosis during ischemia is associated with neuronal injury. The authors measured brain extracellular H + , PCO 2 and HCO 3 - concentrations during an ischemic event produced by temporary occlusion of the middle or anterior cerebral arterial distributions, with a 10-minute recovery period. Patients who were to undergo craniotomy for cerebrovascular surgery were recruited for the study. A probe that measures PCO 2 , pH, and temperature was inserted into tissue at risk for ischemia during temporary arterial occlusion. As a control for this treatment, PaCO 2 was increased 10 mm Hg in five patients over a 10-minute period. Under baseline conditions, there was no difference in arterial blood pressure, blood gas levels, or brain temperature between patients who underwent temporary arterial occlusion or those in whom hypercapnia was induced. In patients in whom hypercapnia was induced, H + , PCO 2 , and HCO 3 - concentrations increased and all values returned to baseline levels within 10 minutes. In 10 patients who underwent a median 9-minute arterial occlusion, transient ischemia was seen with an increase in tissue H + and PCO 2 levels of 100% and 60%, respectively, and a 20% decrease in HCO 3 -levels. After a 10-minute postischemic recovery, only PCO 2 had returned to baseline levels. These results are consistent with a rapid equilibration of lactic acidosis across the cell membrane during ischemia which decreases HCO 3 - concentration. After ischemia, extracellular acidosis may be prolonged because of the extrusion of H + from the cell by membrane ion exchange." @default.
- W2090417259 created "2016-06-24" @default.
- W2090417259 creator A5011267811 @default.
- W2090417259 creator A5015528048 @default.
- W2090417259 creator A5060276061 @default.
- W2090417259 creator A5068219778 @default.
- W2090417259 date "1997-05-01" @default.
- W2090417259 modified "2023-10-13" @default.
- W2090417259 title "Brain tissue acid-base changes during ischemia" @default.
- W2090417259 cites W2014287841 @default.
- W2090417259 cites W2027141849 @default.
- W2090417259 cites W2033879792 @default.
- W2090417259 cites W2048788380 @default.
- W2090417259 cites W2087922149 @default.
- W2090417259 cites W2395033230 @default.
- W2090417259 cites W2400819742 @default.
- W2090417259 cites W954963073 @default.
- W2090417259 doi "https://doi.org/10.3171/foc.1997.2.5.5" @default.
- W2090417259 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15096003" @default.
- W2090417259 hasPublicationYear "1997" @default.
- W2090417259 type Work @default.
- W2090417259 sameAs 2090417259 @default.
- W2090417259 citedByCount "4" @default.
- W2090417259 countsByYear W20904172592012 @default.
- W2090417259 countsByYear W20904172592021 @default.
- W2090417259 crossrefType "journal-article" @default.
- W2090417259 hasAuthorship W2090417259A5011267811 @default.
- W2090417259 hasAuthorship W2090417259A5015528048 @default.
- W2090417259 hasAuthorship W2090417259A5060276061 @default.
- W2090417259 hasAuthorship W2090417259A5068219778 @default.
- W2090417259 hasBestOaLocation W20904172591 @default.
- W2090417259 hasConcept C126322002 @default.
- W2090417259 hasConcept C164705383 @default.
- W2090417259 hasConcept C185592680 @default.
- W2090417259 hasConcept C2113261 @default.
- W2090417259 hasConcept C2776268601 @default.
- W2090417259 hasConcept C2777037550 @default.
- W2090417259 hasConcept C2778553927 @default.
- W2090417259 hasConcept C2779537118 @default.
- W2090417259 hasConcept C2780317664 @default.
- W2090417259 hasConcept C28406088 @default.
- W2090417259 hasConcept C42219234 @default.
- W2090417259 hasConcept C541997718 @default.
- W2090417259 hasConcept C55493867 @default.
- W2090417259 hasConcept C71924100 @default.
- W2090417259 hasConceptScore W2090417259C126322002 @default.
- W2090417259 hasConceptScore W2090417259C164705383 @default.
- W2090417259 hasConceptScore W2090417259C185592680 @default.
- W2090417259 hasConceptScore W2090417259C2113261 @default.
- W2090417259 hasConceptScore W2090417259C2776268601 @default.
- W2090417259 hasConceptScore W2090417259C2777037550 @default.
- W2090417259 hasConceptScore W2090417259C2778553927 @default.
- W2090417259 hasConceptScore W2090417259C2779537118 @default.
- W2090417259 hasConceptScore W2090417259C2780317664 @default.
- W2090417259 hasConceptScore W2090417259C28406088 @default.
- W2090417259 hasConceptScore W2090417259C42219234 @default.
- W2090417259 hasConceptScore W2090417259C541997718 @default.
- W2090417259 hasConceptScore W2090417259C55493867 @default.
- W2090417259 hasConceptScore W2090417259C71924100 @default.
- W2090417259 hasIssue "5" @default.
- W2090417259 hasLocation W20904172591 @default.
- W2090417259 hasLocation W20904172592 @default.
- W2090417259 hasOpenAccess W2090417259 @default.
- W2090417259 hasPrimaryLocation W20904172591 @default.
- W2090417259 hasRelatedWork W1982433963 @default.
- W2090417259 hasRelatedWork W1993072600 @default.
- W2090417259 hasRelatedWork W2172037562 @default.
- W2090417259 hasRelatedWork W2285672337 @default.
- W2090417259 hasRelatedWork W2412014884 @default.
- W2090417259 hasRelatedWork W2497785827 @default.
- W2090417259 hasRelatedWork W3090738329 @default.
- W2090417259 hasRelatedWork W3168822392 @default.
- W2090417259 hasRelatedWork W4236818914 @default.
- W2090417259 hasRelatedWork W4252994144 @default.
- W2090417259 hasVolume "2" @default.
- W2090417259 isParatext "false" @default.
- W2090417259 isRetracted "false" @default.
- W2090417259 magId "2090417259" @default.
- W2090417259 workType "article" @default.