FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090432093> ?p ?o ?g. }

• W2090432093 endingPage "762" @default.
• W2090432093 startingPage "754" @default.
• W2090432093 abstract "Endocrine cells, such as H295R have been widely used to study secretion of steroid and other hormones. Exocytosis-dependent hormone release is accompanied by an increase in plasma membrane surface area and a decrease in vesicle content. Recovery of vesicles and decrease in plasma membrane area is achieved by endocytotic processes. These changes in the extent of the surface area lead to morphological changes which can be determined by label-free real-time impedance measurements. Exo- and endocytosis have been described to be triggered by activation of L-type Ca2+ channels. The present study demonstrates that activation of L-type calcium channels induces prolonged oscillating changes in cellular impedance. The data support the hypothesis that a tight regulation of the intracellular Ca2+ concentration is a prerequisite for the observed cellular impedance oscillations. Furthermore evidence is presented for a mechanism in which the oscillations depend on a Ca2+-triggered calmodulin-dependent cascade involving myosin light chain kinase, nonmuscle myosin II and ultimately actin polymerization, a known determinant for cell shape changes and exocytosis in secretory cells. The described assay provides a method to determine continuously prolonged changes in cellular morphology such as exo/endocytosis cycles." @default.
• W2090432093 created "2016-06-24" @default.
• W2090432093 creator A5003370897 @default.
• W2090432093 creator A5019334806 @default.
• W2090432093 creator A5036003677 @default.
• W2090432093 creator A5056696050 @default.
• W2090432093 creator A5067067051 @default.
• W2090432093 creator A5086341035 @default.
• W2090432093 creator A5087404983 @default.
• W2090432093 date "2011-05-01" @default.
• W2090432093 modified "2023-10-14" @default.
• W2090432093 title "Real-time cellular impedance measurements detect Ca2+ channel-dependent oscillations of morphology in human H295R adrenoma cells" @default.
• W2090432093 cites W105877377 @default.
• W2090432093 cites W1897916153 @default.
• W2090432093 cites W1963952222 @default.
• W2090432093 cites W1979589683 @default.
• W2090432093 cites W1986865899 @default.
• W2090432093 cites W1992326206 @default.
• W2090432093 cites W1996069880 @default.
• W2090432093 cites W2001005374 @default.
• W2090432093 cites W2002099221 @default.
• W2090432093 cites W2009582775 @default.
• W2090432093 cites W2015942581 @default.
• W2090432093 cites W2036469729 @default.
• W2090432093 cites W2055015857 @default.
• W2090432093 cites W2055948011 @default.
• W2090432093 cites W2061396971 @default.
• W2090432093 cites W2062053225 @default.
• W2090432093 cites W2063697882 @default.
• W2090432093 cites W2070569763 @default.
• W2090432093 cites W2071756952 @default.
• W2090432093 cites W2084766450 @default.
• W2090432093 cites W2085091421 @default.
• W2090432093 cites W2086178662 @default.
• W2090432093 cites W2095994722 @default.
• W2090432093 cites W2108250147 @default.
• W2090432093 cites W2109068089 @default.
• W2090432093 cites W2124320835 @default.
• W2090432093 cites W2132346644 @default.
• W2090432093 cites W2133443775 @default.
• W2090432093 cites W2134160775 @default.
• W2090432093 cites W2140657586 @default.
• W2090432093 cites W2144744785 @default.
• W2090432093 cites W2162384842 @default.
• W2090432093 cites W2163139372 @default.
• W2090432093 cites W2164681906 @default.
• W2090432093 cites W2912991414 @default.
• W2090432093 cites W39219210 @default.
• W2090432093 doi "https://doi.org/10.1016/j.bbamcr.2011.01.016" @default.
• W2090432093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21262275" @default.
• W2090432093 hasPublicationYear "2011" @default.
• W2090432093 type Work @default.
• W2090432093 sameAs 2090432093 @default.
• W2090432093 citedByCount "14" @default.
• W2090432093 countsByYear W20904320932012 @default.
• W2090432093 countsByYear W20904320932013 @default.
• W2090432093 countsByYear W20904320932015 @default.
• W2090432093 countsByYear W20904320932016 @default.
• W2090432093 countsByYear W20904320932019 @default.
• W2090432093 countsByYear W20904320932020 @default.
• W2090432093 countsByYear W20904320932021 @default.
• W2090432093 countsByYear W20904320932023 @default.
• W2090432093 crossrefType "journal-article" @default.
• W2090432093 hasAuthorship W2090432093A5003370897 @default.
• W2090432093 hasAuthorship W2090432093A5019334806 @default.
• W2090432093 hasAuthorship W2090432093A5036003677 @default.
• W2090432093 hasAuthorship W2090432093A5056696050 @default.
• W2090432093 hasAuthorship W2090432093A5067067051 @default.
• W2090432093 hasAuthorship W2090432093A5086341035 @default.
• W2090432093 hasAuthorship W2090432093A5087404983 @default.
• W2090432093 hasConcept C12554922 @default.
• W2090432093 hasConcept C130316041 @default.
• W2090432093 hasConcept C1491633281 @default.
• W2090432093 hasConcept C175969161 @default.
• W2090432093 hasConcept C185592680 @default.
• W2090432093 hasConcept C28005876 @default.
• W2090432093 hasConcept C41625074 @default.
• W2090432093 hasConcept C49039625 @default.
• W2090432093 hasConcept C55493867 @default.
• W2090432093 hasConcept C79879829 @default.
• W2090432093 hasConcept C86803240 @default.
• W2090432093 hasConcept C95444343 @default.
• W2090432093 hasConceptScore W2090432093C12554922 @default.
• W2090432093 hasConceptScore W2090432093C130316041 @default.
• W2090432093 hasConceptScore W2090432093C1491633281 @default.
• W2090432093 hasConceptScore W2090432093C175969161 @default.
• W2090432093 hasConceptScore W2090432093C185592680 @default.
• W2090432093 hasConceptScore W2090432093C28005876 @default.
• W2090432093 hasConceptScore W2090432093C41625074 @default.
• W2090432093 hasConceptScore W2090432093C49039625 @default.
• W2090432093 hasConceptScore W2090432093C55493867 @default.
• W2090432093 hasConceptScore W2090432093C79879829 @default.
• W2090432093 hasConceptScore W2090432093C86803240 @default.
• W2090432093 hasConceptScore W2090432093C95444343 @default.
• W2090432093 hasIssue "5" @default.
• W2090432093 hasLocation W20904320931 @default.
• W2090432093 hasLocation W20904320932 @default.
• W2090432093 hasOpenAccess W2090432093 @default.

• next