Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090435562> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2090435562 endingPage "71" @default.
- W2090435562 startingPage "65" @default.
- W2090435562 abstract "Recently, we have developed a SCID mouse model in which circulating red blood cells (RBC) are entirely substituted with RBCs from other animals like bovine (Bo) or human (Hu). The relatively short life time, especially of Hu-RBCs, in the SCID mouse, however, is a major obstacle in this model. The present study was performed to examine whether a low-toxic sulfated chitin, carboxymethyl chitin III (SCM-chitin III), which has heparin-like structures in the molecule (heparinoid), could inhibit the Hu-RBC clearance in RBC-transfused SCID mice. When Hu-RBCs were transfused simultaneously with SCM-chitin III, their life time in the blood circulation was prolonged significantly. Sulfated chitosan (S-chitosan) showed only a weak decelerating activity on the clearance of Hu-RBCs. Carboxymethyl chitin (CM-chitin), which was used as an unsulfated control compound, had no effect on the Hu-RBC clearance. Another sulfated polysaccharide, dextran sulfate, though this showed some adverse effects, such as anti-coagulant and anti-platelet aggregation, also exhibited a potent decelerating activity on Hu-RBC clearance. Clearance deceleration by these sulfated polysaccharides was primarily attributable to the inhibition of RBC uptake by cultured macrophages." @default.
- W2090435562 created "2016-06-24" @default.
- W2090435562 creator A5004375935 @default.
- W2090435562 creator A5010612929 @default.
- W2090435562 creator A5011862590 @default.
- W2090435562 creator A5038199270 @default.
- W2090435562 creator A5055200015 @default.
- W2090435562 date "1995-02-01" @default.
- W2090435562 modified "2023-09-27" @default.
- W2090435562 title "A sulfated chitin, SCM-chitin III, inhibits the clearance of human erythrocytes from the blood circulation in erythrocyte-transfused SCID mice" @default.
- W2090435562 cites W1470989986 @default.
- W2090435562 cites W1586162668 @default.
- W2090435562 cites W1840424754 @default.
- W2090435562 cites W1971637669 @default.
- W2090435562 cites W1975157857 @default.
- W2090435562 cites W1979724852 @default.
- W2090435562 cites W1980168986 @default.
- W2090435562 cites W1989877475 @default.
- W2090435562 cites W1991278650 @default.
- W2090435562 cites W2010519150 @default.
- W2090435562 cites W2033657863 @default.
- W2090435562 cites W2036235431 @default.
- W2090435562 cites W2059414534 @default.
- W2090435562 cites W2060400750 @default.
- W2090435562 cites W2074339977 @default.
- W2090435562 cites W2074650786 @default.
- W2090435562 cites W2078413488 @default.
- W2090435562 cites W2079801738 @default.
- W2090435562 cites W2088533667 @default.
- W2090435562 cites W2172982769 @default.
- W2090435562 cites W2173547083 @default.
- W2090435562 cites W2319956677 @default.
- W2090435562 cites W2325919619 @default.
- W2090435562 cites W4313308945 @default.
- W2090435562 cites W70759473 @default.
- W2090435562 doi "https://doi.org/10.1016/0162-3109(95)00045-u" @default.
- W2090435562 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7768673" @default.
- W2090435562 hasPublicationYear "1995" @default.
- W2090435562 type Work @default.
- W2090435562 sameAs 2090435562 @default.
- W2090435562 citedByCount "9" @default.
- W2090435562 countsByYear W20904355622017 @default.
- W2090435562 countsByYear W20904355622019 @default.
- W2090435562 crossrefType "journal-article" @default.
- W2090435562 hasAuthorship W2090435562A5004375935 @default.
- W2090435562 hasAuthorship W2090435562A5010612929 @default.
- W2090435562 hasAuthorship W2090435562A5011862590 @default.
- W2090435562 hasAuthorship W2090435562A5038199270 @default.
- W2090435562 hasAuthorship W2090435562A5055200015 @default.
- W2090435562 hasConcept C100817775 @default.
- W2090435562 hasConcept C155138218 @default.
- W2090435562 hasConcept C185592680 @default.
- W2090435562 hasConcept C203014093 @default.
- W2090435562 hasConcept C2776557347 @default.
- W2090435562 hasConcept C2777557582 @default.
- W2090435562 hasConcept C2779732960 @default.
- W2090435562 hasConcept C2779863229 @default.
- W2090435562 hasConcept C2781088250 @default.
- W2090435562 hasConcept C55493867 @default.
- W2090435562 hasConcept C86803240 @default.
- W2090435562 hasConcept C89560881 @default.
- W2090435562 hasConceptScore W2090435562C100817775 @default.
- W2090435562 hasConceptScore W2090435562C155138218 @default.
- W2090435562 hasConceptScore W2090435562C185592680 @default.
- W2090435562 hasConceptScore W2090435562C203014093 @default.
- W2090435562 hasConceptScore W2090435562C2776557347 @default.
- W2090435562 hasConceptScore W2090435562C2777557582 @default.
- W2090435562 hasConceptScore W2090435562C2779732960 @default.
- W2090435562 hasConceptScore W2090435562C2779863229 @default.
- W2090435562 hasConceptScore W2090435562C2781088250 @default.
- W2090435562 hasConceptScore W2090435562C55493867 @default.
- W2090435562 hasConceptScore W2090435562C86803240 @default.
- W2090435562 hasConceptScore W2090435562C89560881 @default.
- W2090435562 hasIssue "1" @default.
- W2090435562 hasLocation W20904355621 @default.
- W2090435562 hasLocation W20904355622 @default.
- W2090435562 hasOpenAccess W2090435562 @default.
- W2090435562 hasPrimaryLocation W20904355621 @default.
- W2090435562 hasRelatedWork W1138747202 @default.
- W2090435562 hasRelatedWork W1912808485 @default.
- W2090435562 hasRelatedWork W2001852846 @default.
- W2090435562 hasRelatedWork W2004118163 @default.
- W2090435562 hasRelatedWork W2039954703 @default.
- W2090435562 hasRelatedWork W2090435562 @default.
- W2090435562 hasRelatedWork W2378859811 @default.
- W2090435562 hasRelatedWork W2418628830 @default.
- W2090435562 hasRelatedWork W3178483573 @default.
- W2090435562 hasRelatedWork W4293339596 @default.
- W2090435562 hasVolume "29" @default.
- W2090435562 isParatext "false" @default.
- W2090435562 isRetracted "false" @default.
- W2090435562 magId "2090435562" @default.
- W2090435562 workType "article" @default.