FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090450640> ?p ?o ?g. }

• W2090450640 endingPage "39" @default.
• W2090450640 startingPage "36" @default.
• W2090450640 abstract "p53 Arg72Pro, MDM2 T309G, and CCND1 G870A are functional single-nucleotide polymorphisms (SNPs) in key genes that regulate apoptosis and cell cycle. Variant genotypes of these SNPs have been associated with increased risk and earlier age of onset in some cancers. We investigated the association of these SNPs with susceptibility to esophageal adenocarcinoma in a large, North American case-control study. Three hundred and twelve cases and 454 cancer-free controls recruited in Boston, USA were genotyped for each of the three SNPs, and demographic and clinical data were collected. Genotype frequencies for each of the three SNPs did not deviate from the Hardy-Weinberg equilibrium, and did not differ between cases and controls. Odds ratios (OR), adjusted for clinical risk factors, for the homozygous variant genotypes were 0.99 (95% confidence interval [CI] 0.57-1.72) for p53 Pro/Pro, 0.81 (95% CI 0.52-1.28) for MDM2 G/G, and 0.97 (95% CI 0.64-1.49) for CCND1 A/A. The analysis was adequately powered (80%) to detect ORs of 1.37, 1.35, and 1.34 for each SNP, respectively. In contrast to the results of smaller published studies, no association between p53 Arg72Pro, MDM2 T309G, and CCND1 G870A SNPs and susceptibility to esophageal adenocarcinoma, age of onset, or stage of disease at diagnosis was detected." @default.
• W2090450640 created "2016-06-24" @default.
• W2090450640 creator A5003723404 @default.
• W2090450640 creator A5017947396 @default.
• W2090450640 creator A5023531951 @default.
• W2090450640 creator A5035243580 @default.
• W2090450640 creator A5037996246 @default.
• W2090450640 creator A5044565573 @default.
• W2090450640 creator A5060911347 @default.
• W2090450640 creator A5064382279 @default.
• W2090450640 creator A5072282829 @default.
• W2090450640 creator A5083104090 @default.
• W2090450640 creator A5085322716 @default.
• W2090450640 creator A5085349348 @default.
• W2090450640 creator A5091331939 @default.
• W2090450640 date "2010-01-01" @default.
• W2090450640 modified "2023-10-16" @default.
• W2090450640 title "p53 Arg72Pro, MDM2 T309GandCCND1 G870Apolymorphisms are not associated with susceptibility to esophageal adenocarcinoma" @default.
• W2090450640 cites W1983409515 @default.
• W2090450640 cites W1984959915 @default.
• W2090450640 cites W2003141511 @default.
• W2090450640 cites W2004129093 @default.
• W2090450640 cites W2005400333 @default.
• W2090450640 cites W2010452001 @default.
• W2090450640 cites W2020769895 @default.
• W2090450640 cites W2032057758 @default.
• W2090450640 cites W2042601043 @default.
• W2090450640 cites W2096391113 @default.
• W2090450640 cites W2106331836 @default.
• W2090450640 cites W2109154917 @default.
• W2090450640 cites W2112743619 @default.
• W2090450640 cites W2113236360 @default.
• W2090450640 cites W2132723376 @default.
• W2090450640 cites W2133990678 @default.
• W2090450640 cites W2139172234 @default.
• W2090450640 cites W2145436734 @default.
• W2090450640 cites W2158347281 @default.
• W2090450640 cites W2170428165 @default.
• W2090450640 doi "https://doi.org/10.1111/j.1442-2050.2009.00960.x" @default.
• W2090450640 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2866140" @default.
• W2090450640 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19302219" @default.
• W2090450640 hasPublicationYear "2010" @default.
• W2090450640 type Work @default.
• W2090450640 sameAs 2090450640 @default.
• W2090450640 citedByCount "32" @default.
• W2090450640 countsByYear W20904506402012 @default.
• W2090450640 countsByYear W20904506402013 @default.
• W2090450640 countsByYear W20904506402014 @default.
• W2090450640 countsByYear W20904506402015 @default.
• W2090450640 countsByYear W20904506402016 @default.
• W2090450640 countsByYear W20904506402017 @default.
• W2090450640 countsByYear W20904506402019 @default.
• W2090450640 countsByYear W20904506402020 @default.
• W2090450640 crossrefType "journal-article" @default.
• W2090450640 hasAuthorship W2090450640A5003723404 @default.
• W2090450640 hasAuthorship W2090450640A5017947396 @default.
• W2090450640 hasAuthorship W2090450640A5023531951 @default.
• W2090450640 hasAuthorship W2090450640A5035243580 @default.
• W2090450640 hasAuthorship W2090450640A5037996246 @default.
• W2090450640 hasAuthorship W2090450640A5044565573 @default.
• W2090450640 hasAuthorship W2090450640A5060911347 @default.
• W2090450640 hasAuthorship W2090450640A5064382279 @default.
• W2090450640 hasAuthorship W2090450640A5072282829 @default.
• W2090450640 hasAuthorship W2090450640A5083104090 @default.
• W2090450640 hasAuthorship W2090450640A5085322716 @default.
• W2090450640 hasAuthorship W2090450640A5085349348 @default.
• W2090450640 hasAuthorship W2090450640A5091331939 @default.
• W2090450640 hasBestOaLocation W20904506402 @default.
• W2090450640 hasConcept C104317684 @default.
• W2090450640 hasConcept C121608353 @default.
• W2090450640 hasConcept C126322002 @default.
• W2090450640 hasConcept C135763542 @default.
• W2090450640 hasConcept C139275648 @default.
• W2090450640 hasConcept C143998085 @default.
• W2090450640 hasConcept C146304588 @default.
• W2090450640 hasConcept C153209595 @default.
• W2090450640 hasConcept C156957248 @default.
• W2090450640 hasConcept C197754878 @default.
• W2090450640 hasConcept C2776192174 @default.
• W2090450640 hasConcept C2779742542 @default.
• W2090450640 hasConcept C2781182431 @default.
• W2090450640 hasConcept C44249647 @default.
• W2090450640 hasConcept C54355233 @default.
• W2090450640 hasConcept C71924100 @default.
• W2090450640 hasConcept C86803240 @default.
• W2090450640 hasConcept C90924648 @default.
• W2090450640 hasConceptScore W2090450640C104317684 @default.
• W2090450640 hasConceptScore W2090450640C121608353 @default.
• W2090450640 hasConceptScore W2090450640C126322002 @default.
• W2090450640 hasConceptScore W2090450640C135763542 @default.
• W2090450640 hasConceptScore W2090450640C139275648 @default.
• W2090450640 hasConceptScore W2090450640C143998085 @default.
• W2090450640 hasConceptScore W2090450640C146304588 @default.
• W2090450640 hasConceptScore W2090450640C153209595 @default.
• W2090450640 hasConceptScore W2090450640C156957248 @default.
• W2090450640 hasConceptScore W2090450640C197754878 @default.
• W2090450640 hasConceptScore W2090450640C2776192174 @default.
• W2090450640 hasConceptScore W2090450640C2779742542 @default.

• next