FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090464854> ?p ?o ?g. }

• W2090464854 endingPage "865" @default.
• W2090464854 startingPage "857" @default.
• W2090464854 abstract "Context: Spices have been used as food adjuncts and in folklore for ages. Inhibition of key enzymes (α-amylase and α-glucosidase) involved in the digestion of starch and protection against free radicals and lipid peroxidation in pancreas could be part of the therapeutic approach towards the management of hyperglycemia and dietary phenolics have shown promising potentials.Objective: This study investigated and compared the inhibitory properties of aqueous extracts of some tropical spices: Xylopia aethiopica [Dun.] A. Rich (Annonaceae), Monodora myristica (Gaertn.) Dunal (Annonaceae), Syzygium aromaticum [L.] Merr. et Perry (Myrtaceae), Piper guineense Schumach. et Thonn (Piperaceae), Aframomum danielli K. Schum (Zingiberaceae) and Aframomum melegueta (Rosc.) K. Schum (Zingiberaceae) against α-amylase, α-glucosidase, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and sodium nitroprusside (SNP)-induced lipid peroxidation in rat pancreas - in vitro using different spectrophotometric method.Materials and methods: Aqueous extract of the spices was prepared and the ability of the spice extracts to inhibit α-amylase, α-glucosidase, DPPH radicals and SNP-induced lipid peroxidation in rat pancreas - in vitro was investigated using various spectrophotometric methods.Result: All the spice extracts inhibited α-amylase (IC50 = 2.81–4.83 mg/mL), α-glucosidase (IC50 = 2.02–3.52 mg/mL), DPPH radicals (EC50 = 15.47–17.38 mg/mL) and SNP-induced lipid peroxidation (14.17–94.38%), with the highest α-amylase & α-glucosidase inhibitory actions and DPPH radical scavenging ability exhibited by X. aethiopica, A. danielli and S. aromaticum, respectively. Also, the spices possess high total phenol (0.88–1.3 mg/mL) and flavonoid (0.24–0.52 mg/mL) contents with A. melegueta having the highest total phenolic and flavonoid contents.Discussion and conclusion: The inhibitory effects of the spice extracts on α-amylase, α-glucosidase, DPPH radicals and SNP-induced lipid peroxidation in pancreas (in vitro) could be attributed to the presence of biologically active phytochemicals such as phenolics and some non-phenolic constituents of the spices. Furthermore, these spices may exert their anti-diabetic properties through the mechanism of enzyme inhibition, free radicals scavenging ability and prevention of lipid peroxidation." @default.
• W2090464854 created "2016-06-24" @default.
• W2090464854 creator A5013871427 @default.
• W2090464854 creator A5030437818 @default.
• W2090464854 date "2012-04-06" @default.
• W2090464854 modified "2023-10-01" @default.
• W2090464854 title "Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water extractable phytochemicals from some tropical spices" @default.
• W2090464854 cites W1524482367 @default.
• W2090464854 cites W1559903407 @default.
• W2090464854 cites W1960608858 @default.
• W2090464854 cites W1979189704 @default.
• W2090464854 cites W1983310681 @default.
• W2090464854 cites W1992725304 @default.
• W2090464854 cites W1995947856 @default.
• W2090464854 cites W1997740032 @default.
• W2090464854 cites W2009864041 @default.
• W2090464854 cites W2010169277 @default.
• W2090464854 cites W2011181885 @default.
• W2090464854 cites W2014418136 @default.
• W2090464854 cites W2016935594 @default.
• W2090464854 cites W2020411326 @default.
• W2090464854 cites W2020554367 @default.
• W2090464854 cites W2024150029 @default.
• W2090464854 cites W2030843716 @default.
• W2090464854 cites W2031245034 @default.
• W2090464854 cites W2035069368 @default.
• W2090464854 cites W2039067313 @default.
• W2090464854 cites W2043428504 @default.
• W2090464854 cites W2043969520 @default.
• W2090464854 cites W2052931215 @default.
• W2090464854 cites W2059467226 @default.
• W2090464854 cites W2059684897 @default.
• W2090464854 cites W2062347046 @default.
• W2090464854 cites W2067375085 @default.
• W2090464854 cites W2071931890 @default.
• W2090464854 cites W2079341791 @default.
• W2090464854 cites W2082767535 @default.
• W2090464854 cites W2083535249 @default.
• W2090464854 cites W2083556212 @default.
• W2090464854 cites W2132681327 @default.
• W2090464854 cites W2135236802 @default.
• W2090464854 cites W2138465005 @default.
• W2090464854 cites W2140568827 @default.
• W2090464854 cites W2141581995 @default.
• W2090464854 cites W2146933403 @default.
• W2090464854 cites W2152252699 @default.
• W2090464854 cites W2157425406 @default.
• W2090464854 cites W2161849974 @default.
• W2090464854 cites W2335171012 @default.
• W2090464854 cites W2471605942 @default.
• W2090464854 cites W32239657 @default.
• W2090464854 doi "https://doi.org/10.3109/13880209.2011.641022" @default.
• W2090464854 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22480175" @default.
• W2090464854 hasPublicationYear "2012" @default.
• W2090464854 type Work @default.
• W2090464854 sameAs 2090464854 @default.
• W2090464854 citedByCount "79" @default.
• W2090464854 countsByYear W20904648542012 @default.
• W2090464854 countsByYear W20904648542013 @default.
• W2090464854 countsByYear W20904648542014 @default.
• W2090464854 countsByYear W20904648542015 @default.
• W2090464854 countsByYear W20904648542016 @default.
• W2090464854 countsByYear W20904648542017 @default.
• W2090464854 countsByYear W20904648542018 @default.
• W2090464854 countsByYear W20904648542019 @default.
• W2090464854 countsByYear W20904648542020 @default.
• W2090464854 countsByYear W20904648542021 @default.
• W2090464854 countsByYear W20904648542022 @default.
• W2090464854 countsByYear W20904648542023 @default.
• W2090464854 crossrefType "journal-article" @default.
• W2090464854 hasAuthorship W2090464854A5013871427 @default.
• W2090464854 hasAuthorship W2090464854A5030437818 @default.
• W2090464854 hasBestOaLocation W20904648541 @default.
• W2090464854 hasConcept C134550120 @default.
• W2090464854 hasConcept C151730666 @default.
• W2090464854 hasConcept C170835558 @default.
• W2090464854 hasConcept C181199279 @default.
• W2090464854 hasConcept C185592680 @default.
• W2090464854 hasConcept C2776789170 @default.
• W2090464854 hasConcept C2778004101 @default.
• W2090464854 hasConcept C2779343474 @default.
• W2090464854 hasConcept C2780829032 @default.
• W2090464854 hasConcept C2781401929 @default.
• W2090464854 hasConcept C31903555 @default.
• W2090464854 hasConcept C55493867 @default.
• W2090464854 hasConcept C556039675 @default.
• W2090464854 hasConcept C71924100 @default.
• W2090464854 hasConcept C86803240 @default.
• W2090464854 hasConceptScore W2090464854C134550120 @default.
• W2090464854 hasConceptScore W2090464854C151730666 @default.
• W2090464854 hasConceptScore W2090464854C170835558 @default.
• W2090464854 hasConceptScore W2090464854C181199279 @default.
• W2090464854 hasConceptScore W2090464854C185592680 @default.
• W2090464854 hasConceptScore W2090464854C2776789170 @default.
• W2090464854 hasConceptScore W2090464854C2778004101 @default.
• W2090464854 hasConceptScore W2090464854C2779343474 @default.
• W2090464854 hasConceptScore W2090464854C2780829032 @default.
• W2090464854 hasConceptScore W2090464854C2781401929 @default.

• next