Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090468215> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2090468215 endingPage "298" @default.
- W2090468215 startingPage "293" @default.
- W2090468215 abstract "We reviewed 49 patients in whom a diagnosis of Huntington's disease (HD) seemed possible on clinical grounds, but who gave no history of definitely affected relatives. In 32 with the typical clinical features of HD (progressive chorea and dementia, postural instability, abnormal initiation of saccadic eye movements), the diagnosis was confirmed in 7 patients who had had autopsies, affected relatives were found in 5 others, and HD remained probable in a further 13 who were reexamined. In the 17 with a less typical clinical picture, a diagnosis of HD appeared most likely in 2; other causes for chorea such as cerebrovascular disease, neuroacanthocytosis, recrudescence of Sydenham's chorea, and drug-induced tardive dyskinesia could be invoked in the remainder. We conclude that the likelihood of HD in a patient with the typical clinical features of this disorder but no history of affected relatives is at least 75%, which for practical purposes implies a risk to their children hardly less than in familial HD. The most plausible explanations for seemingly sporadic patients with HD are nonpaternity and mild, late-onset disease that is overlooked by other family members." @default.
- W2090468215 created "2016-06-24" @default.
- W2090468215 creator A5002796221 @default.
- W2090468215 creator A5038881110 @default.
- W2090468215 creator A5043875235 @default.
- W2090468215 creator A5067600400 @default.
- W2090468215 creator A5071867646 @default.
- W2090468215 date "1992-03-01" @default.
- W2090468215 modified "2023-10-16" @default.
- W2090468215 title "A follow-up study of isolated cases of suspected Huntington's disease" @default.
- W2090468215 cites W2000853059 @default.
- W2090468215 cites W2020854310 @default.
- W2090468215 cites W2041793727 @default.
- W2090468215 cites W2043192442 @default.
- W2090468215 cites W2044040323 @default.
- W2090468215 cites W2063774541 @default.
- W2090468215 cites W2082056883 @default.
- W2090468215 cites W2082208664 @default.
- W2090468215 cites W2102347956 @default.
- W2090468215 cites W2112499843 @default.
- W2090468215 cites W2128627950 @default.
- W2090468215 cites W2133967356 @default.
- W2090468215 cites W2170219032 @default.
- W2090468215 cites W2172635594 @default.
- W2090468215 doi "https://doi.org/10.1002/ana.410310311" @default.
- W2090468215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1386209" @default.
- W2090468215 hasPublicationYear "1992" @default.
- W2090468215 type Work @default.
- W2090468215 sameAs 2090468215 @default.
- W2090468215 citedByCount "19" @default.
- W2090468215 countsByYear W20904682152012 @default.
- W2090468215 crossrefType "journal-article" @default.
- W2090468215 hasAuthorship W2090468215A5002796221 @default.
- W2090468215 hasAuthorship W2090468215A5038881110 @default.
- W2090468215 hasAuthorship W2090468215A5043875235 @default.
- W2090468215 hasAuthorship W2090468215A5067600400 @default.
- W2090468215 hasAuthorship W2090468215A5071867646 @default.
- W2090468215 hasConcept C118552586 @default.
- W2090468215 hasConcept C126322002 @default.
- W2090468215 hasConcept C15744967 @default.
- W2090468215 hasConcept C187212893 @default.
- W2090468215 hasConcept C2776412080 @default.
- W2090468215 hasConcept C2778261627 @default.
- W2090468215 hasConcept C2778868616 @default.
- W2090468215 hasConcept C2779134260 @default.
- W2090468215 hasConcept C2779158372 @default.
- W2090468215 hasConcept C2779483572 @default.
- W2090468215 hasConcept C2779734285 @default.
- W2090468215 hasConcept C2780405171 @default.
- W2090468215 hasConcept C2780647506 @default.
- W2090468215 hasConcept C2781179581 @default.
- W2090468215 hasConcept C71924100 @default.
- W2090468215 hasConceptScore W2090468215C118552586 @default.
- W2090468215 hasConceptScore W2090468215C126322002 @default.
- W2090468215 hasConceptScore W2090468215C15744967 @default.
- W2090468215 hasConceptScore W2090468215C187212893 @default.
- W2090468215 hasConceptScore W2090468215C2776412080 @default.
- W2090468215 hasConceptScore W2090468215C2778261627 @default.
- W2090468215 hasConceptScore W2090468215C2778868616 @default.
- W2090468215 hasConceptScore W2090468215C2779134260 @default.
- W2090468215 hasConceptScore W2090468215C2779158372 @default.
- W2090468215 hasConceptScore W2090468215C2779483572 @default.
- W2090468215 hasConceptScore W2090468215C2779734285 @default.
- W2090468215 hasConceptScore W2090468215C2780405171 @default.
- W2090468215 hasConceptScore W2090468215C2780647506 @default.
- W2090468215 hasConceptScore W2090468215C2781179581 @default.
- W2090468215 hasConceptScore W2090468215C71924100 @default.
- W2090468215 hasIssue "3" @default.
- W2090468215 hasLocation W20904682151 @default.
- W2090468215 hasLocation W20904682152 @default.
- W2090468215 hasOpenAccess W2090468215 @default.
- W2090468215 hasPrimaryLocation W20904682151 @default.
- W2090468215 hasRelatedWork W1497198897 @default.
- W2090468215 hasRelatedWork W1972382836 @default.
- W2090468215 hasRelatedWork W1996163753 @default.
- W2090468215 hasRelatedWork W2071774402 @default.
- W2090468215 hasRelatedWork W2090468215 @default.
- W2090468215 hasRelatedWork W2212845025 @default.
- W2090468215 hasRelatedWork W2980733815 @default.
- W2090468215 hasRelatedWork W2995971655 @default.
- W2090468215 hasRelatedWork W3027194062 @default.
- W2090468215 hasRelatedWork W2063242260 @default.
- W2090468215 hasVolume "31" @default.
- W2090468215 isParatext "false" @default.
- W2090468215 isRetracted "false" @default.
- W2090468215 magId "2090468215" @default.
- W2090468215 workType "article" @default.