Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090544680> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2090544680 endingPage "67" @default.
- W2090544680 startingPage "59" @default.
- W2090544680 abstract "Mucous membrane pemphigoid (MMP), also known as cicatricial pemphigoid (CP), is an autoimmune mucocutaneous, blistering disease which can lead to blindness and/or death from sudden asphyxiation, secondary to a scarring process. Conventional therapy for the treatment of MMP consists of high-dose systemic corticosteroids and/or immunosuppressive agents. Some patients do not respond to these treatments and develop multiple serious side effects, which can be potentially fatal. In such patients, alternative treatment modalities are needed. This study presents the use of intravenous immunoglobulin (IVIg) therapy in 15 patients with severe MMP whose disease was nonresponsive to the prolonged use of high-dose systemic corticosteroids and immunosuppressive agents and who developed multiple side effects to them. All 15 patients received an IVIg dose of 1–2 g/kg/cycle. The following objective parameters were used to assess the clinical outcome pre- and post-IVIg therapy: number of side effects, frequencies of recurrences and relapses, duration and total dosage of prednisone therapy, and the quality of life. The differences in these variables between the pre- and post-IVIg data were statistically analyzed using the SAS UNIVARIATE software running the two-sided Wilcoxon signed-rank and sign tests. A statistically significant difference was observed between pre- and post-IVIg therapy data when comparing the aforementioned variables. All 15 patients had an effective clinical response, were able to discontinue previous systemic therapies, and eventually achieved a prolonged clinical remission. IVIg improved the quality of life in all 15 patients and demonstrated a steroid-sparing effect. No serious side effects were observed. IVIg therapy is a safe and effective alternative modality in the treatment of patients with nonresponsive and progressive MMP and can induce a sustained clinical remission." @default.
- W2090544680 created "2016-06-24" @default.
- W2090544680 creator A5010341209 @default.
- W2090544680 creator A5061811305 @default.
- W2090544680 creator A5077847799 @default.
- W2090544680 date "2002-01-01" @default.
- W2090544680 modified "2023-10-17" @default.
- W2090544680 title "Intravenous Immunoglobulin Therapy in Patients with Multiple Mucosal Involvement in Mucous Membrane Pemphigoid" @default.
- W2090544680 cites W1552230426 @default.
- W2090544680 cites W188853335 @default.
- W2090544680 cites W1939229386 @default.
- W2090544680 cites W1942654056 @default.
- W2090544680 cites W1997916949 @default.
- W2090544680 cites W2007765706 @default.
- W2090544680 cites W2013526408 @default.
- W2090544680 cites W2026129217 @default.
- W2090544680 cites W2036134560 @default.
- W2090544680 cites W2044208450 @default.
- W2090544680 cites W2053730359 @default.
- W2090544680 cites W2079903880 @default.
- W2090544680 cites W2116462505 @default.
- W2090544680 cites W2125076165 @default.
- W2090544680 cites W2130264575 @default.
- W2090544680 cites W2137825212 @default.
- W2090544680 cites W2143693718 @default.
- W2090544680 cites W2150084951 @default.
- W2090544680 cites W2167825887 @default.
- W2090544680 cites W4211091472 @default.
- W2090544680 cites W4233426510 @default.
- W2090544680 doi "https://doi.org/10.1006/clim.2001.5150" @default.
- W2090544680 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11781068" @default.
- W2090544680 hasPublicationYear "2002" @default.
- W2090544680 type Work @default.
- W2090544680 sameAs 2090544680 @default.
- W2090544680 citedByCount "56" @default.
- W2090544680 countsByYear W20905446802012 @default.
- W2090544680 countsByYear W20905446802013 @default.
- W2090544680 countsByYear W20905446802016 @default.
- W2090544680 countsByYear W20905446802017 @default.
- W2090544680 countsByYear W20905446802018 @default.
- W2090544680 countsByYear W20905446802019 @default.
- W2090544680 countsByYear W20905446802021 @default.
- W2090544680 countsByYear W20905446802023 @default.
- W2090544680 crossrefType "journal-article" @default.
- W2090544680 hasAuthorship W2090544680A5010341209 @default.
- W2090544680 hasAuthorship W2090544680A5061811305 @default.
- W2090544680 hasAuthorship W2090544680A5077847799 @default.
- W2090544680 hasConcept C126322002 @default.
- W2090544680 hasConcept C141071460 @default.
- W2090544680 hasConcept C156662089 @default.
- W2090544680 hasConcept C159654299 @default.
- W2090544680 hasConcept C203014093 @default.
- W2090544680 hasConcept C2778075117 @default.
- W2090544680 hasConcept C2778720950 @default.
- W2090544680 hasConcept C2779134260 @default.
- W2090544680 hasConcept C2779252107 @default.
- W2090544680 hasConcept C2779890267 @default.
- W2090544680 hasConcept C2909916134 @default.
- W2090544680 hasConcept C71924100 @default.
- W2090544680 hasConcept C90924648 @default.
- W2090544680 hasConceptScore W2090544680C126322002 @default.
- W2090544680 hasConceptScore W2090544680C141071460 @default.
- W2090544680 hasConceptScore W2090544680C156662089 @default.
- W2090544680 hasConceptScore W2090544680C159654299 @default.
- W2090544680 hasConceptScore W2090544680C203014093 @default.
- W2090544680 hasConceptScore W2090544680C2778075117 @default.
- W2090544680 hasConceptScore W2090544680C2778720950 @default.
- W2090544680 hasConceptScore W2090544680C2779134260 @default.
- W2090544680 hasConceptScore W2090544680C2779252107 @default.
- W2090544680 hasConceptScore W2090544680C2779890267 @default.
- W2090544680 hasConceptScore W2090544680C2909916134 @default.
- W2090544680 hasConceptScore W2090544680C71924100 @default.
- W2090544680 hasConceptScore W2090544680C90924648 @default.
- W2090544680 hasIssue "1" @default.
- W2090544680 hasLocation W20905446801 @default.
- W2090544680 hasLocation W20905446802 @default.
- W2090544680 hasOpenAccess W2090544680 @default.
- W2090544680 hasPrimaryLocation W20905446801 @default.
- W2090544680 hasRelatedWork W2037757700 @default.
- W2090544680 hasRelatedWork W2060755196 @default.
- W2090544680 hasRelatedWork W2073370269 @default.
- W2090544680 hasRelatedWork W2400254164 @default.
- W2090544680 hasRelatedWork W2412390337 @default.
- W2090544680 hasRelatedWork W2954437864 @default.
- W2090544680 hasRelatedWork W3029181686 @default.
- W2090544680 hasRelatedWork W4213043791 @default.
- W2090544680 hasRelatedWork W4308531276 @default.
- W2090544680 hasRelatedWork W3110658294 @default.
- W2090544680 hasVolume "102" @default.
- W2090544680 isParatext "false" @default.
- W2090544680 isRetracted "false" @default.
- W2090544680 magId "2090544680" @default.
- W2090544680 workType "article" @default.