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• W2090580330 abstract "Traditional IMRT process consists of two steps (1) Estimation of ideal intensity distribution (2) Obtaining deliverable intensity distribution using a leaf sequencing algorithm. An alternative technique consists of a single step in which multileaf collimator (MLC) delivery constraints are incorporated into the optimization process. This technique is called deliverable optimization. The goal of this work was to determine if the IMRT plans obtained with dynamic MLC (DMLC) based and step and shoot (SS) based deliverable optimization techniques were equivalent in terms of target coverage and critical structure sparing. Four head and neck (HN) and four prostate patients were selected for this study. IMRT plans were created using (1) in-house DMLC based deliverable optimization software and (2) SS based deliverable software called direct machine parameter optimization (DMPO) available in Pinnacle3 system. While HN IMRT plans utilized nine coplanar beams, all prostate plans involved seven coplanar beams. DMLC plans are composed of large number segments. For DMPO plans, the maximum number of segments per beam was initially set to ten (e.g., for 9 split HN fields, 180 segments). To evaluate the effect of fewer segments the number of segments (DMPOless) were reduced to 90 for HN and 70 for prostate and the plans were optimized with the same constraints. The dose-volume criteria evaluated for the target and critical structures are shown in Table 1. The results of this analysis are shown in Table 1. IMRT plans using DMLC were comparable to DMPO. The maximum % volume difference between the DMLC and DMPO plans were 0.71% in terms of target volume coverage and 2.33% in terms of sparing of the critical structures over all cases. Similarly the maximum % volume difference between the DMLC and DMPOless plans were 2.44% in terms of target volume coverage and 2.94% in terms of sparing of the critical structures. In addition the monitor units for DMPO were seen to decrease by ∼29% for HN and ∼35% for prostate cases. DMPO provides plans equivalent in quality to deliverable DMLC. Reducing the number of segments by half (DMPOless) did not significantly affect the quality of the plans. The number of monitor units significantly decreased when using the step and shoot deliverable optimization i.e. DMPO." @default.
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• W2090580330 date "2007-11-01" @default.
• W2090580330 modified "2023-09-26" @default.
• W2090580330 title "Assessment of IMRT Plans Optimized With Deliverable Step and Shoot (SS) and Dynamic MLC (DMLC) Techniques" @default.
• W2090580330 doi "https://doi.org/10.1016/j.ijrobp.2007.07.2103" @default.
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