Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090597613> ?p ?o ?g. }
- W2090597613 endingPage "358" @default.
- W2090597613 startingPage "352" @default.
- W2090597613 abstract "Context Early-life factors (including intrauterine growth retardation) may influence the development of type 2 diabetes. We postulated that birth size is associated with cortisol levels, which itself could alter serum adipomyokines (i.e. adiponectin, IGF-I, myostatin) and glucose metabolism. Design An observational study with 60 Afro-Caribbean young adults from a birth cohort. Measurements Fasting blood was drawn for serum adiponectin, IGF-I and myostatin. A frequently sampled intravenous glucose tolerance test measured insulin sensitivity (SI), acute insulin response (AIRg), disposition index (DI) and glucose effectiveness (Sg). Body composition was assessed by dual-energy X-ray absorptiometry. Salivary cortisol was collected at home at 0800 and 2300 h. Sex-adjusted correlations were used to explore the relationships between birth size, cortisol and the metabolic variables. Results The participants were 55% male, mean age 23·1 ± 0·5 years. Birth weight correlated positively with 2300-h cortisol (P = 0·04), although not after adjusting for gestational age. Gestational age was correlated with 2300 h cortisol (r = 0·38, P = 0·03), even after adjusting for birth weight (P = 0·02). 2300 h cortisol was not associated with adiponectin, IGF-I, myostatin, SI, AIRg or DI, but was negatively correlated with Sg (r = −0·30, P = 0·05) even after adjusting for birth and adult anthropometry. Adiponectin, IGF-I and myostatin were unrelated to glucose metabolism. Conclusions Gestational age is associated with higher nocturnal cortisol, which in turn is associated with lower glucose effectiveness in adulthood. Higher glucose effectiveness could therefore be a compensatory mechanism to improve glucose uptake." @default.
- W2090597613 created "2016-06-24" @default.
- W2090597613 creator A5013017819 @default.
- W2090597613 creator A5029738136 @default.
- W2090597613 creator A5035941373 @default.
- W2090597613 creator A5055249722 @default.
- W2090597613 creator A5069145599 @default.
- W2090597613 creator A5075638087 @default.
- W2090597613 creator A5077793733 @default.
- W2090597613 creator A5085083937 @default.
- W2090597613 date "2014-08-07" @default.
- W2090597613 modified "2023-09-25" @default.
- W2090597613 title "Early-life factors are associated with nocturnal cortisol and glucose effectiveness in Afro-Caribbean young adults" @default.
- W2090597613 cites W1557910385 @default.
- W2090597613 cites W1965612664 @default.
- W2090597613 cites W1973535547 @default.
- W2090597613 cites W1974022347 @default.
- W2090597613 cites W1975898092 @default.
- W2090597613 cites W1985124060 @default.
- W2090597613 cites W2000368607 @default.
- W2090597613 cites W2003889314 @default.
- W2090597613 cites W2004438440 @default.
- W2090597613 cites W2014257689 @default.
- W2090597613 cites W2022133717 @default.
- W2090597613 cites W2024185170 @default.
- W2090597613 cites W2024418686 @default.
- W2090597613 cites W2032631738 @default.
- W2090597613 cites W2040450294 @default.
- W2090597613 cites W2040567344 @default.
- W2090597613 cites W2047200302 @default.
- W2090597613 cites W2051855513 @default.
- W2090597613 cites W2053467811 @default.
- W2090597613 cites W2067132822 @default.
- W2090597613 cites W2080883436 @default.
- W2090597613 cites W2087313135 @default.
- W2090597613 cites W2091314811 @default.
- W2090597613 cites W2102132607 @default.
- W2090597613 cites W2115004636 @default.
- W2090597613 cites W2118020419 @default.
- W2090597613 cites W2127283734 @default.
- W2090597613 cites W2133256471 @default.
- W2090597613 cites W2139379883 @default.
- W2090597613 cites W2154175838 @default.
- W2090597613 cites W2169926462 @default.
- W2090597613 cites W2185328935 @default.
- W2090597613 cites W2325329777 @default.
- W2090597613 cites W2602374010 @default.
- W2090597613 doi "https://doi.org/10.1111/cen.12537" @default.
- W2090597613 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24988876" @default.
- W2090597613 hasPublicationYear "2014" @default.
- W2090597613 type Work @default.
- W2090597613 sameAs 2090597613 @default.
- W2090597613 citedByCount "3" @default.
- W2090597613 countsByYear W20905976132016 @default.
- W2090597613 countsByYear W20905976132022 @default.
- W2090597613 crossrefType "journal-article" @default.
- W2090597613 hasAuthorship W2090597613A5013017819 @default.
- W2090597613 hasAuthorship W2090597613A5029738136 @default.
- W2090597613 hasAuthorship W2090597613A5035941373 @default.
- W2090597613 hasAuthorship W2090597613A5055249722 @default.
- W2090597613 hasAuthorship W2090597613A5069145599 @default.
- W2090597613 hasAuthorship W2090597613A5075638087 @default.
- W2090597613 hasAuthorship W2090597613A5077793733 @default.
- W2090597613 hasAuthorship W2090597613A5085083937 @default.
- W2090597613 hasConcept C126322002 @default.
- W2090597613 hasConcept C134018914 @default.
- W2090597613 hasConcept C151730666 @default.
- W2090597613 hasConcept C2776782570 @default.
- W2090597613 hasConcept C2777391703 @default.
- W2090597613 hasConcept C2778376644 @default.
- W2090597613 hasConcept C2779234561 @default.
- W2090597613 hasConcept C2779306644 @default.
- W2090597613 hasConcept C2779343474 @default.
- W2090597613 hasConcept C2780938740 @default.
- W2090597613 hasConcept C54355233 @default.
- W2090597613 hasConcept C66322754 @default.
- W2090597613 hasConcept C71924100 @default.
- W2090597613 hasConcept C86803240 @default.
- W2090597613 hasConceptScore W2090597613C126322002 @default.
- W2090597613 hasConceptScore W2090597613C134018914 @default.
- W2090597613 hasConceptScore W2090597613C151730666 @default.
- W2090597613 hasConceptScore W2090597613C2776782570 @default.
- W2090597613 hasConceptScore W2090597613C2777391703 @default.
- W2090597613 hasConceptScore W2090597613C2778376644 @default.
- W2090597613 hasConceptScore W2090597613C2779234561 @default.
- W2090597613 hasConceptScore W2090597613C2779306644 @default.
- W2090597613 hasConceptScore W2090597613C2779343474 @default.
- W2090597613 hasConceptScore W2090597613C2780938740 @default.
- W2090597613 hasConceptScore W2090597613C54355233 @default.
- W2090597613 hasConceptScore W2090597613C66322754 @default.
- W2090597613 hasConceptScore W2090597613C71924100 @default.
- W2090597613 hasConceptScore W2090597613C86803240 @default.
- W2090597613 hasIssue "3" @default.
- W2090597613 hasLocation W20905976131 @default.
- W2090597613 hasLocation W20905976132 @default.
- W2090597613 hasOpenAccess W2090597613 @default.
- W2090597613 hasPrimaryLocation W20905976131 @default.
- W2090597613 hasRelatedWork W1982589044 @default.