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• W2090600910 abstract "Abstract Introduction The outcome of ABO ‐incompatible kidney transplantation ( ABO i KT ) has improved and is now comparable to that of ABO ‐compatible kidney transplantation ( ABO c KT ). However, ABO i KT may be associated with a higher risk of postoperative bleeding than ABO c KT . Methods Seventy patients with ABO i KT were divided into a bleeding group (n = 9) and non‐bleeding group (n = 61). General, immunologic, and hematological characteristics were compared to identify the risk factors for postoperative bleeding. Results Pre‐emptive transplantation and a high pre‐transplant blood urea nitrogen level were more common in the bleeding group (p = 0.0176 and 0.023, respectively). A high anti‐ ABO antibody titer after plasmapheresis (median, ≥16; p = 0.0226), a low platelet count of ≤100 000/mm 3 after plasmapheresis (p = 0.0289), a prolonged activated partial thromboplastin time (p = 0.0073), and impaired platelet function (p = 0.0274) were associated with an increased risk of bleeding after ABO i KT . Conclusion Postoperative bleeding after ABO i KT was difficult to control and increased the risk of immediate graft loss (p = 0.015). Our results suggest that changes in coagulability associated with uremia and plasmapheresis may increase the risk of bleeding after ABO i KT ." @default.
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• W2090600910 date "2015-04-01" @default.
• W2090600910 modified "2023-10-02" @default.
• W2090600910 title "Risk factors for postoperative bleeding in ABO-incompatible kidney transplantation" @default.
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• W2090600910 doi "https://doi.org/10.1111/ctr.12525" @default.
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