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- W2090623897 abstract "A method is derived for computing mean gene frequencies and absorption probabilities in populations of variable size, where the probabilities of transition between the alternative population sizes can be specified. A haploid model is adopted, with two alleles at a single locus undergoing weak selection. The results are approximate, involving the first terms in a matrix series, in which the dimensions of the matrices are the number of alternative sizes the population can take, rather than the total number of population size and gene frequency states in the full model. A diffusion-equation approximation is also considered which leads to a very simple formula. It is valid when population sizes and selective values are large, but have small coefficients of variation, and when a stationary distribution of population sizes is reached quickly. A model of selective values assuming a normal distribution of fitness is used to illustrate the results." @default.
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- W2090623897 date "1972-03-01" @default.
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- W2090623897 title "Probability of fixation of genes in populations of variable size" @default.
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- W2090623897 doi "https://doi.org/10.1016/0040-5809(72)90032-9" @default.
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