Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090628617> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2090628617 endingPage "696" @default.
- W2090628617 startingPage "690" @default.
- W2090628617 abstract "The fragile sites of human chromosomes are specific sites that are characterized by a tendency to show gaps, multiradial figures, acentric fragments, and deleted chromosomes on microscopy. These characteristics seem to reflect an inherent fragility at the site, although the underlying biochemical cause of fragile sites is unknown. Investigators have proposed several categories of fragile sites: “rare” or “heritable,” “common,” and “constitutive.” Although the clinical significance of most fragile sites is unknown, fragile site Xq27.3 is associated with one form of X-linked mental retardation. In this article, the three types of chromosome fragile sites are described, and their possible relevance to chromosomal breakage that results in birth defects or cancer is discussed. The fragile sites of human chromosomes are specific sites that are characterized by a tendency to show gaps, multiradial figures, acentric fragments, and deleted chromosomes on microscopy. These characteristics seem to reflect an inherent fragility at the site, although the underlying biochemical cause of fragile sites is unknown. Investigators have proposed several categories of fragile sites: “rare” or “heritable,” “common,” and “constitutive.” Although the clinical significance of most fragile sites is unknown, fragile site Xq27.3 is associated with one form of X-linked mental retardation. In this article, the three types of chromosome fragile sites are described, and their possible relevance to chromosomal breakage that results in birth defects or cancer is discussed." @default.
- W2090628617 created "2016-06-24" @default.
- W2090628617 creator A5080023085 @default.
- W2090628617 date "1985-10-01" @default.
- W2090628617 modified "2023-10-18" @default.
- W2090628617 title "Fragile Sites on Human Chromosomes: Description and Clinical Significance" @default.
- W2090628617 cites W1974993967 @default.
- W2090628617 cites W1984890836 @default.
- W2090628617 cites W1995089109 @default.
- W2090628617 cites W2002607580 @default.
- W2090628617 cites W2011468912 @default.
- W2090628617 cites W2032748338 @default.
- W2090628617 cites W2038108954 @default.
- W2090628617 cites W2039827091 @default.
- W2090628617 cites W2054219981 @default.
- W2090628617 cites W2063654777 @default.
- W2090628617 cites W2071577201 @default.
- W2090628617 cites W2074226874 @default.
- W2090628617 cites W2076786539 @default.
- W2090628617 cites W2089659280 @default.
- W2090628617 cites W2092359582 @default.
- W2090628617 cites W2092441446 @default.
- W2090628617 cites W2092887637 @default.
- W2090628617 cites W2096110794 @default.
- W2090628617 cites W2166133600 @default.
- W2090628617 cites W2416618226 @default.
- W2090628617 cites W3022009864 @default.
- W2090628617 cites W3146832232 @default.
- W2090628617 cites W4205470054 @default.
- W2090628617 doi "https://doi.org/10.1016/s0025-6196(12)60745-9" @default.
- W2090628617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3897734" @default.
- W2090628617 hasPublicationYear "1985" @default.
- W2090628617 type Work @default.
- W2090628617 sameAs 2090628617 @default.
- W2090628617 citedByCount "8" @default.
- W2090628617 crossrefType "journal-article" @default.
- W2090628617 hasAuthorship W2090628617A5080023085 @default.
- W2090628617 hasConcept C104317684 @default.
- W2090628617 hasConcept C142724271 @default.
- W2090628617 hasConcept C174475383 @default.
- W2090628617 hasConcept C2777630245 @default.
- W2090628617 hasConcept C3020422209 @default.
- W2090628617 hasConcept C30481170 @default.
- W2090628617 hasConcept C35158069 @default.
- W2090628617 hasConcept C53226629 @default.
- W2090628617 hasConcept C54355233 @default.
- W2090628617 hasConcept C60449816 @default.
- W2090628617 hasConcept C63363279 @default.
- W2090628617 hasConcept C71924100 @default.
- W2090628617 hasConcept C72391661 @default.
- W2090628617 hasConcept C80116771 @default.
- W2090628617 hasConcept C86803240 @default.
- W2090628617 hasConceptScore W2090628617C104317684 @default.
- W2090628617 hasConceptScore W2090628617C142724271 @default.
- W2090628617 hasConceptScore W2090628617C174475383 @default.
- W2090628617 hasConceptScore W2090628617C2777630245 @default.
- W2090628617 hasConceptScore W2090628617C3020422209 @default.
- W2090628617 hasConceptScore W2090628617C30481170 @default.
- W2090628617 hasConceptScore W2090628617C35158069 @default.
- W2090628617 hasConceptScore W2090628617C53226629 @default.
- W2090628617 hasConceptScore W2090628617C54355233 @default.
- W2090628617 hasConceptScore W2090628617C60449816 @default.
- W2090628617 hasConceptScore W2090628617C63363279 @default.
- W2090628617 hasConceptScore W2090628617C71924100 @default.
- W2090628617 hasConceptScore W2090628617C72391661 @default.
- W2090628617 hasConceptScore W2090628617C80116771 @default.
- W2090628617 hasConceptScore W2090628617C86803240 @default.
- W2090628617 hasIssue "10" @default.
- W2090628617 hasLocation W20906286171 @default.
- W2090628617 hasLocation W20906286172 @default.
- W2090628617 hasOpenAccess W2090628617 @default.
- W2090628617 hasPrimaryLocation W20906286171 @default.
- W2090628617 hasRelatedWork W177223050 @default.
- W2090628617 hasRelatedWork W1967097889 @default.
- W2090628617 hasRelatedWork W1982227356 @default.
- W2090628617 hasRelatedWork W1998537613 @default.
- W2090628617 hasRelatedWork W2052028037 @default.
- W2090628617 hasRelatedWork W2068266928 @default.
- W2090628617 hasRelatedWork W2070551500 @default.
- W2090628617 hasRelatedWork W2090628617 @default.
- W2090628617 hasRelatedWork W2186041148 @default.
- W2090628617 hasRelatedWork W2747932505 @default.
- W2090628617 hasVolume "60" @default.
- W2090628617 isParatext "false" @default.
- W2090628617 isRetracted "false" @default.
- W2090628617 magId "2090628617" @default.
- W2090628617 workType "article" @default.