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- W2090631062 abstract "Covalently closed circular plasmid DNA was modified by benzo[a]pyrene diolepoxide and incubated with partially purified fractions of the Escherichia coli uvr+ gene products. Strand breaks were introduced into the modified DNA by the uvrABC endonuclease; on average, one break was formed for each bound benzo[a]pyrene residue in the DNA. These results are direct evidence that benzo[a]pyrene adducts in DNA are acted upon by the same repair enzyme as those that handle UV-induced lesions in DNA." @default.
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- W2090631062 date "1983-06-01" @default.
- W2090631062 modified "2023-10-11" @default.
- W2090631062 title "Strand-break formation in DNA modified by benzo[a]pyrene diolepoxide Quantitative cleavage by Escherichia coli uvr ABC endonuclease" @default.
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- W2090631062 doi "https://doi.org/10.1016/0167-8817(83)90036-6" @default.
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