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• W2090632762 abstract "Objective A twin study design was used to examine the genetic validity of attention-deficit hyperactivity disorder (ADHD)–related phenotypes. Method Questionnaires covering ADHD symptoms were sent to the families of 2,846 school-age twins. Parent-rated symptoms were obtained for 2,082 twin pairs and teacher-rated symptoms were available for 1,470 twin pairs. Results Broadly defined parent-rated, teacher-rated, and “pervasive” (both parent-and teacher-rated) ADHD categories were found to be highly heritable. Significant shared environmental effects were also detected for teacher-rated ADHD. A common genetic factor was found to have a modest influence on both parent-and teacher-rated symptom scores and categories, but additional genetic and environmental influences were also found for teacher-rated ADHD. Consistent with previous findings, ADHD symptom scores were again found to be highly heritable. Maternal contrast effects were found for the Rutter A scale items but could not be detected for the DuPaul ADHD rating scale. Conclusions Broadly defined pervasive ADHD appears to be as heritable as ADHD behaviors defined by maternal reports alone. A common genetic factor influences maternally rated and teacher-rated ADHD but does not account for all of the genetic variance for teacher-rated ADHD. ADHD symptom scores are highly heritable, and maternal contrast effects appear to vary for different measures." @default.
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• W2090632762 date "2000-12-01" @default.
• W2090632762 modified "2023-09-27" @default.
• W2090632762 title "Does the Definition of ADHD Affect Heritability?" @default.
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• W2090632762 doi "https://doi.org/10.1097/00004583-200012000-00015" @default.
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