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- W2090655275 abstract "Forty-three patients with evaluable metastatic breast cancer refractory to hormonal agents and extensive combination chemotherapy including doxorubicin were treated with mitomycin, 20 mg/m2 intravenously every 6 weeks. There were five partial responses (12%) and three minor responses (7%), with a mean time to progression of 5 months and 3.5 months, respectively. Thrombocytopenia was the major dose-limiting toxicity, and myelosuppression was cumulative. Cardiac dysfunction was observed in 12% of patients. Mitomycin had some antitumor activity in this group of metastatic breast cancer patients refractory to extensive combination chemotherapy including doxorubicin." @default.
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- W2090655275 date "1985-11-15" @default.
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- W2090655275 title "Mitomycin in metastatic breast cancer refractory to hormonal and combination chemotherapy" @default.
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- W2090655275 doi "https://doi.org/10.1002/1097-0142(19851115)56:10<2381::aid-cncr2820561006>3.0.co;2-2" @default.
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