FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090660414> ?p ?o ?g. }

• W2090660414 endingPage "304" @default.
• W2090660414 startingPage "297" @default.
• W2090660414 abstract "In a comparative study, we show that human artificial chromosome (HAC) vectors based on alpha-satellite (alphoid) DNA from chromosome 17 but not the Y chromosome regularly form HACs in HT1080 human cells. We constructed four structurally similar HAC vectors, two with chromosome 17 or Y alphoid DNA (17alpha, Yalpha) and two with 17alpha or Yalpha and the hypoxanthine guanine phosphoribosyltransferase locus (HPRT1). The 17alpha HAC vectors generated artificial minichromosomes in 32-79% of the HT1080 clones screened, compared with only approximately 4% for the Yalpha HAC vectors, indicating that Yalpha is inefficient at forming a de novo centromere. The 17alpha HAC vectors produced megabase-sized, circular HACs containing multiple copies of alphoid fragments (60-250 kb) interspersed with either vector or HPRT1 DNA. The 17alpha-HPRT1 HACs were less stable than those with 17alpha only, and these results may influence the design of new HAC gene transfer vectors." @default.
• W2090660414 created "2016-06-24" @default.
• W2090660414 creator A5003910166 @default.
• W2090660414 creator A5015707587 @default.
• W2090660414 creator A5016557941 @default.
• W2090660414 creator A5034180687 @default.
• W2090660414 creator A5047873642 @default.
• W2090660414 creator A5067240012 @default.
• W2090660414 creator A5080529453 @default.
• W2090660414 date "2002-03-01" @default.
• W2090660414 modified "2023-10-17" @default.
• W2090660414 title "Efficiency of de Novo Centromere Formation in Human Artificial Chromosomes" @default.
• W2090660414 cites W1541417296 @default.
• W2090660414 cites W1545110015 @default.
• W2090660414 cites W1967317736 @default.
• W2090660414 cites W1972485008 @default.
• W2090660414 cites W1986395573 @default.
• W2090660414 cites W1993002815 @default.
• W2090660414 cites W1995004188 @default.
• W2090660414 cites W1999837153 @default.
• W2090660414 cites W2009362775 @default.
• W2090660414 cites W2010655741 @default.
• W2090660414 cites W2014200281 @default.
• W2090660414 cites W2023972660 @default.
• W2090660414 cites W2033338722 @default.
• W2090660414 cites W2036627966 @default.
• W2090660414 cites W2043363977 @default.
• W2090660414 cites W2043542212 @default.
• W2090660414 cites W2044403261 @default.
• W2090660414 cites W2050252789 @default.
• W2090660414 cites W2066884699 @default.
• W2090660414 cites W2069089403 @default.
• W2090660414 cites W2077003408 @default.
• W2090660414 cites W2091035877 @default.
• W2090660414 cites W2091477263 @default.
• W2090660414 cites W2093673239 @default.
• W2090660414 cites W2106833455 @default.
• W2090660414 cites W2129876916 @default.
• W2090660414 cites W2135159992 @default.
• W2090660414 cites W2143084318 @default.
• W2090660414 cites W2145921551 @default.
• W2090660414 cites W2157027464 @default.
• W2090660414 cites W2163542193 @default.
• W2090660414 cites W2318761112 @default.
• W2090660414 cites W4240624574 @default.
• W2090660414 cites W4361865646 @default.
• W2090660414 doi "https://doi.org/10.1006/geno.2002.6704" @default.
• W2090660414 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11863359" @default.
• W2090660414 hasPublicationYear "2002" @default.
• W2090660414 type Work @default.
• W2090660414 sameAs 2090660414 @default.
• W2090660414 citedByCount "72" @default.
• W2090660414 countsByYear W20906604142012 @default.
• W2090660414 countsByYear W20906604142013 @default.
• W2090660414 countsByYear W20906604142015 @default.
• W2090660414 countsByYear W20906604142016 @default.
• W2090660414 countsByYear W20906604142017 @default.
• W2090660414 countsByYear W20906604142018 @default.
• W2090660414 countsByYear W20906604142019 @default.
• W2090660414 countsByYear W20906604142020 @default.
• W2090660414 countsByYear W20906604142021 @default.
• W2090660414 countsByYear W20906604142023 @default.
• W2090660414 crossrefType "journal-article" @default.
• W2090660414 hasAuthorship W2090660414A5003910166 @default.
• W2090660414 hasAuthorship W2090660414A5015707587 @default.
• W2090660414 hasAuthorship W2090660414A5016557941 @default.
• W2090660414 hasAuthorship W2090660414A5034180687 @default.
• W2090660414 hasAuthorship W2090660414A5047873642 @default.
• W2090660414 hasAuthorship W2090660414A5067240012 @default.
• W2090660414 hasAuthorship W2090660414A5080529453 @default.
• W2090660414 hasConcept C104317684 @default.
• W2090660414 hasConcept C132144397 @default.
• W2090660414 hasConcept C153911025 @default.
• W2090660414 hasConcept C30481170 @default.
• W2090660414 hasConcept C40767141 @default.
• W2090660414 hasConcept C54355233 @default.
• W2090660414 hasConcept C552990157 @default.
• W2090660414 hasConcept C63491729 @default.
• W2090660414 hasConcept C84597430 @default.
• W2090660414 hasConcept C86803240 @default.
• W2090660414 hasConcept C92087593 @default.
• W2090660414 hasConceptScore W2090660414C104317684 @default.
• W2090660414 hasConceptScore W2090660414C132144397 @default.
• W2090660414 hasConceptScore W2090660414C153911025 @default.
• W2090660414 hasConceptScore W2090660414C30481170 @default.
• W2090660414 hasConceptScore W2090660414C40767141 @default.
• W2090660414 hasConceptScore W2090660414C54355233 @default.
• W2090660414 hasConceptScore W2090660414C552990157 @default.
• W2090660414 hasConceptScore W2090660414C63491729 @default.
• W2090660414 hasConceptScore W2090660414C84597430 @default.
• W2090660414 hasConceptScore W2090660414C86803240 @default.
• W2090660414 hasConceptScore W2090660414C92087593 @default.
• W2090660414 hasIssue "3" @default.
• W2090660414 hasLocation W20906604141 @default.
• W2090660414 hasLocation W20906604142 @default.
• W2090660414 hasOpenAccess W2090660414 @default.
• W2090660414 hasPrimaryLocation W20906604141 @default.
• W2090660414 hasRelatedWork W1886625688 @default.

• next