FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090692711> ?p ?o ?g. }

• W2090692711 endingPage "1043" @default.
• W2090692711 startingPage "1032" @default.
• W2090692711 abstract "Osteoblasts arise from mesenchymal stem cells and differentiate to become osteoid-secreting cells. However, little is known about these cells during their stages of differentiation. One reason for this lack of information is that there is no reliable method to identify osteoblasts as they mature. One method that has been used successfully with other cell types is the identification of plasma membrane-expressed differentiation antigens. The Ly-6 multigene family encodes differentiation antigens originally detected on lymphoid cells. Primary murine osteoblasts and the osteoblast-like MC3T3 cell line were examined for expression of Ly-6 antigens by flow cytometry. Primary osteoblasts and MC3T3 cells constitutively expressed both Ly-6A and Ly-6C antigens, although Ly-6C was much less abundant. Antigen expression was markedly increased by pretreating the cells with interferon-alpha/beta or -gamma. Northern blot analysis revealed constitutively expression of Ly-6 messenger RNA that was up-regulated by interferon treatment. Pretreatment of the cells with transforming growth factor-beta 1 or 1,25-dihydroxyvitamin D3 diminished constitutive Ly-6 expression. Ly-6 was localized intracellularly to the Golgi complex. The current results demonstrate that mature osteoblasts express on their cell surface specific Ly-6 antigens in a pattern that distinguishes them from the surrounding bone marrow cells. These studies represent the first identification of osteoblast differentiation antigens that can be directly related to cells within the hematopoietic lineage. By identifying similar antigens, osteoblasts at various stages of differentiation may be identified, isolated, and characterized." @default.
• W2090692711 created "2016-06-24" @default.
• W2090692711 creator A5004481896 @default.
• W2090692711 creator A5006861896 @default.
• W2090692711 creator A5026559034 @default.
• W2090692711 creator A5027818103 @default.
• W2090692711 creator A5051093934 @default.
• W2090692711 creator A5062933215 @default.
• W2090692711 date "1994-09-01" @default.
• W2090692711 modified "2023-09-27" @default.
• W2090692711 title "Expression and regulation of Ly-6 differentiation antigens by murine osteoblasts." @default.
• W2090692711 cites W1531350089 @default.
• W2090692711 cites W1538729663 @default.
• W2090692711 cites W1555967785 @default.
• W2090692711 cites W1561239140 @default.
• W2090692711 cites W1577532420 @default.
• W2090692711 cites W1588586232 @default.
• W2090692711 cites W1592303205 @default.
• W2090692711 cites W1607802582 @default.
• W2090692711 cites W1611413521 @default.
• W2090692711 cites W1613521572 @default.
• W2090692711 cites W1662521307 @default.
• W2090692711 cites W1699334701 @default.
• W2090692711 cites W1785794626 @default.
• W2090692711 cites W1934308140 @default.
• W2090692711 cites W1944100246 @default.
• W2090692711 cites W1964368968 @default.
• W2090692711 cites W1966258516 @default.
• W2090692711 cites W1973689359 @default.
• W2090692711 cites W1978114185 @default.
• W2090692711 cites W1982156222 @default.
• W2090692711 cites W1988192161 @default.
• W2090692711 cites W1989314759 @default.
• W2090692711 cites W1991027949 @default.
• W2090692711 cites W1994772282 @default.
• W2090692711 cites W1998987370 @default.
• W2090692711 cites W2000746306 @default.
• W2090692711 cites W2003843932 @default.
• W2090692711 cites W2008021821 @default.
• W2090692711 cites W2014935189 @default.
• W2090692711 cites W2016945240 @default.
• W2090692711 cites W2021409342 @default.
• W2090692711 cites W2031523385 @default.
• W2090692711 cites W2035165086 @default.
• W2090692711 cites W2036911556 @default.
• W2090692711 cites W2037293839 @default.
• W2090692711 cites W2038054727 @default.
• W2090692711 cites W2044309960 @default.
• W2090692711 cites W2051877466 @default.
• W2090692711 cites W2053821100 @default.
• W2090692711 cites W2062390235 @default.
• W2090692711 cites W2064498617 @default.
• W2090692711 cites W2067112519 @default.
• W2090692711 cites W2074302787 @default.
• W2090692711 cites W2074362305 @default.
• W2090692711 cites W2077046161 @default.
• W2090692711 cites W2084152511 @default.
• W2090692711 cites W2090666457 @default.
• W2090692711 cites W2095524315 @default.
• W2090692711 cites W2102783765 @default.
• W2090692711 cites W2102945947 @default.
• W2090692711 cites W2104931922 @default.
• W2090692711 cites W2154832626 @default.
• W2090692711 cites W2154992787 @default.
• W2090692711 cites W2156933327 @default.
• W2090692711 cites W2265996776 @default.
• W2090692711 cites W2576734941 @default.
• W2090692711 cites W2605099190 @default.
• W2090692711 cites W2016433761 @default.
• W2090692711 doi "https://doi.org/10.1210/endo.135.3.7520861" @default.
• W2090692711 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7520861" @default.
• W2090692711 hasPublicationYear "1994" @default.
• W2090692711 type Work @default.
• W2090692711 sameAs 2090692711 @default.
• W2090692711 citedByCount "49" @default.
• W2090692711 countsByYear W20906927112012 @default.
• W2090692711 countsByYear W20906927112013 @default.
• W2090692711 countsByYear W20906927112014 @default.
• W2090692711 countsByYear W20906927112015 @default.
• W2090692711 countsByYear W20906927112017 @default.
• W2090692711 countsByYear W20906927112018 @default.
• W2090692711 countsByYear W20906927112019 @default.
• W2090692711 countsByYear W20906927112021 @default.
• W2090692711 crossrefType "journal-article" @default.
• W2090692711 hasAuthorship W2090692711A5004481896 @default.
• W2090692711 hasAuthorship W2090692711A5006861896 @default.
• W2090692711 hasAuthorship W2090692711A5026559034 @default.
• W2090692711 hasAuthorship W2090692711A5027818103 @default.
• W2090692711 hasAuthorship W2090692711A5051093934 @default.
• W2090692711 hasAuthorship W2090692711A5062933215 @default.
• W2090692711 hasConcept C104317684 @default.
• W2090692711 hasConcept C147483822 @default.
• W2090692711 hasConcept C148738053 @default.
• W2090692711 hasConcept C153911025 @default.
• W2090692711 hasConcept C153968139 @default.
• W2090692711 hasConcept C159654299 @default.
• W2090692711 hasConcept C198826908 @default.
• W2090692711 hasConcept C201750760 @default.

• next