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- W2090692796 abstract "Abstract Trifluorothymidine (I) is shown to be hydrolyzed in aqueous solution to form 5-trifluoromethyl-l, 2,3,4-tetrahydropyrimidine-2,4-dione (III). An HPLC method for the determination of III is described, and using this method the rates of decomposition of I in aqueous solution have been investigated. A 1% solution showed 2% breakdown after 2 months at 20°C. From accelerated stability studies it is found that solutions stored at 4°C for 2 years would show 1% degradation." @default.
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- W2090692796 date "1980-03-01" @default.
- W2090692796 modified "2023-09-27" @default.
- W2090692796 title "A high pressure liquid chromatographic method for the determination of trifluorothymidine degradation in aqueous solution" @default.
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- W2090692796 doi "https://doi.org/10.1016/0378-5173(80)90046-0" @default.
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