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- W2090717981 endingPage "466" @default.
- W2090717981 startingPage "451" @default.
- W2090717981 abstract "Cognition is often affected in a variety of neuropsychiatric, neurological, and neurodevelopmental disorders. The neural discriminative response, reflected in mismatch negativity (MMN) and its magnetoencephalographic equivalent (MMNm), has been used as a tool to study a variety of disorders involving auditory cognition. MMN/MMNm is an involuntary brain response to auditory change or, more generally, to pattern regularity violation. For a number of disorders, MMN/MMNm amplitude to sound deviance has been shown to be attenuated or the peak-latency of the component prolonged compared to controls. This general finding suggests that while not serving as a specific marker to any particular disorder, MMN may be useful for understanding factors of cognition in various disorders, and has potential to serve as an indicator of risk. This review presents a brief history of the MMN, followed by a description of how MMN has been used to index auditory processing capability in a range of neuropsychiatric, neurological, and neurodevelopmental disorders. Finally, we suggest future directions for research to further enhance our understanding of the neural substrate of deviance detection that could lead to improvements in the use of MMN as a clinical tool." @default.
- W2090717981 created "2016-06-24" @default.
- W2090717981 creator A5011809654 @default.
- W2090717981 creator A5040933857 @default.
- W2090717981 creator A5085780714 @default.
- W2090717981 creator A5091002324 @default.
- W2090717981 date "2014-05-17" @default.
- W2090717981 modified "2023-10-14" @default.
- W2090717981 title "Mismatch Negativity (MMN) as an Index of Cognitive Dysfunction" @default.
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