Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090739456> ?p ?o ?g. }
- W2090739456 endingPage "688" @default.
- W2090739456 startingPage "669" @default.
- W2090739456 abstract "Proteins derived from human plasma have become critically important therapeutic products since their introduction in the 1940s. In the last 20 years, the tools of molecular biology have provided alternatives to the administration of the natural products. Recombinant analogues of Factor VIII and Factor IX are commercially available, and recombinant forms of other plasma proteins are under development. Genetic engineering also provides the opportunity to modify a natural protein to improve the efficiency with which it can be produced in vitro, or to change its therapeutic profile. More efficient production systems, such as transgenic plants or animals, may yield less costly therapies and a wider availability of products that are now in limited supply. Finally, gene therapy offers the prospect of permanently correcting conditions arising from deficiencies in any one of several plasma proteins, freeing individuals from the need to undergo periodic treatments with exogenous proteins." @default.
- W2090739456 created "2016-06-24" @default.
- W2090739456 creator A5005368985 @default.
- W2090739456 date "2000-12-01" @default.
- W2090739456 modified "2023-09-27" @default.
- W2090739456 title "Biotechnology: alternatives to human plasma-derived therapeutic proteins" @default.
- W2090739456 cites W119292240 @default.
- W2090739456 cites W1426203004 @default.
- W2090739456 cites W1487084354 @default.
- W2090739456 cites W1489224366 @default.
- W2090739456 cites W1489758714 @default.
- W2090739456 cites W1524957948 @default.
- W2090739456 cites W1539046821 @default.
- W2090739456 cites W1558454853 @default.
- W2090739456 cites W1564299213 @default.
- W2090739456 cites W1565788467 @default.
- W2090739456 cites W1585827177 @default.
- W2090739456 cites W1586940012 @default.
- W2090739456 cites W1588193324 @default.
- W2090739456 cites W15974371 @default.
- W2090739456 cites W1598075387 @default.
- W2090739456 cites W1605341503 @default.
- W2090739456 cites W1799277187 @default.
- W2090739456 cites W1847478154 @default.
- W2090739456 cites W18814673 @default.
- W2090739456 cites W1888008068 @default.
- W2090739456 cites W1888325444 @default.
- W2090739456 cites W1964816512 @default.
- W2090739456 cites W1965747253 @default.
- W2090739456 cites W1966625557 @default.
- W2090739456 cites W1967357094 @default.
- W2090739456 cites W1969542542 @default.
- W2090739456 cites W1971613351 @default.
- W2090739456 cites W1973199921 @default.
- W2090739456 cites W1973919938 @default.
- W2090739456 cites W1975141313 @default.
- W2090739456 cites W1978097734 @default.
- W2090739456 cites W1978306920 @default.
- W2090739456 cites W1979575838 @default.
- W2090739456 cites W1989790981 @default.
- W2090739456 cites W1993366862 @default.
- W2090739456 cites W1994194230 @default.
- W2090739456 cites W1994852532 @default.
- W2090739456 cites W1995642515 @default.
- W2090739456 cites W1995822104 @default.
- W2090739456 cites W1996716984 @default.
- W2090739456 cites W1997016178 @default.
- W2090739456 cites W2004406029 @default.
- W2090739456 cites W2005815589 @default.
- W2090739456 cites W2007429292 @default.
- W2090739456 cites W2008267475 @default.
- W2090739456 cites W2009991379 @default.
- W2090739456 cites W2011762615 @default.
- W2090739456 cites W2011767474 @default.
- W2090739456 cites W2015219383 @default.
- W2090739456 cites W2019231516 @default.
- W2090739456 cites W2022615595 @default.
- W2090739456 cites W2023820753 @default.
- W2090739456 cites W2028324631 @default.
- W2090739456 cites W202913011 @default.
- W2090739456 cites W2031311971 @default.
- W2090739456 cites W2037949785 @default.
- W2090739456 cites W2038794567 @default.
- W2090739456 cites W2039911802 @default.
- W2090739456 cites W2040486239 @default.
- W2090739456 cites W2040943601 @default.
- W2090739456 cites W2041076733 @default.
- W2090739456 cites W2043244241 @default.
- W2090739456 cites W2050193680 @default.
- W2090739456 cites W2050510640 @default.
- W2090739456 cites W2055111634 @default.
- W2090739456 cites W2056410434 @default.
- W2090739456 cites W2059849821 @default.
- W2090739456 cites W2062929761 @default.
- W2090739456 cites W2069535685 @default.
- W2090739456 cites W2069578552 @default.
- W2090739456 cites W206975662 @default.
- W2090739456 cites W2070616597 @default.
- W2090739456 cites W2070858323 @default.
- W2090739456 cites W2073305192 @default.
- W2090739456 cites W2075115601 @default.
- W2090739456 cites W2075765271 @default.
- W2090739456 cites W2080971554 @default.
- W2090739456 cites W2082299454 @default.
- W2090739456 cites W2082304984 @default.
- W2090739456 cites W2084083151 @default.
- W2090739456 cites W2089136912 @default.
- W2090739456 cites W2089671802 @default.
- W2090739456 cites W2091463743 @default.
- W2090739456 cites W2091771432 @default.
- W2090739456 cites W2092720597 @default.
- W2090739456 cites W2093662358 @default.
- W2090739456 cites W2114126275 @default.
- W2090739456 cites W2115869789 @default.
- W2090739456 cites W2122892044 @default.
- W2090739456 cites W2136240349 @default.
- W2090739456 cites W2139031305 @default.
- W2090739456 cites W2145969871 @default.