Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090768907> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2090768907 endingPage "272" @default.
- W2090768907 startingPage "265" @default.
- W2090768907 abstract "The use of nonviral plasmid-based gene medicines represents an attractive in vivo gene transfer strategy that is simple and lacks many risks that are inherent to viral systems. Commercialization of gene medicines requires a thorough analysis of business opportunities, unmet clinical needs, competitive products under development, and issues related to intellectual property. Synthetic gene delivery systems are designed to control the location of a gene within the body by affecting distribution and access of a gene expression system to the target cell, and/or recognition by a cell surface receptor and uptake followed by intracellular and nuclear translocation. Plasmid-based gene expression systems are designed to control the level, fidelity, and duration of in vivo production of a therapeutic gene product. This review will provide insights into the potentials of plasmid-based gene therapy and critical evaluation of gene delivery sciences and clinical applications of gene medicines. © 1999 Academic Press." @default.
- W2090768907 created "2016-06-24" @default.
- W2090768907 creator A5031230140 @default.
- W2090768907 date "1996-06-01" @default.
- W2090768907 modified "2023-09-26" @default.
- W2090768907 title "Safety and regulation at the leading edge of biomedical biotechnology" @default.
- W2090768907 cites W1976942362 @default.
- W2090768907 cites W1990276959 @default.
- W2090768907 cites W2010289001 @default.
- W2090768907 cites W2017051909 @default.
- W2090768907 cites W2023375373 @default.
- W2090768907 cites W2067379696 @default.
- W2090768907 cites W2147493341 @default.
- W2090768907 cites W2160710831 @default.
- W2090768907 cites W2321689187 @default.
- W2090768907 cites W4230181722 @default.
- W2090768907 cites W4231286171 @default.
- W2090768907 cites W4240368844 @default.
- W2090768907 cites W4298029310 @default.
- W2090768907 doi "https://doi.org/10.1016/s0958-1669(96)80027-9" @default.
- W2090768907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8785428" @default.
- W2090768907 hasPublicationYear "1996" @default.
- W2090768907 type Work @default.
- W2090768907 sameAs 2090768907 @default.
- W2090768907 citedByCount "12" @default.
- W2090768907 countsByYear W20907689072013 @default.
- W2090768907 countsByYear W20907689072016 @default.
- W2090768907 crossrefType "journal-article" @default.
- W2090768907 hasAuthorship W2090768907A5031230140 @default.
- W2090768907 hasConcept C102230213 @default.
- W2090768907 hasConcept C104317684 @default.
- W2090768907 hasConcept C111599444 @default.
- W2090768907 hasConcept C135983454 @default.
- W2090768907 hasConcept C144133560 @default.
- W2090768907 hasConcept C150194340 @default.
- W2090768907 hasConcept C150903083 @default.
- W2090768907 hasConcept C162853370 @default.
- W2090768907 hasConcept C165864922 @default.
- W2090768907 hasConcept C195286587 @default.
- W2090768907 hasConcept C22744801 @default.
- W2090768907 hasConcept C2780625559 @default.
- W2090768907 hasConcept C54355233 @default.
- W2090768907 hasConcept C70721500 @default.
- W2090768907 hasConcept C86803240 @default.
- W2090768907 hasConceptScore W2090768907C102230213 @default.
- W2090768907 hasConceptScore W2090768907C104317684 @default.
- W2090768907 hasConceptScore W2090768907C111599444 @default.
- W2090768907 hasConceptScore W2090768907C135983454 @default.
- W2090768907 hasConceptScore W2090768907C144133560 @default.
- W2090768907 hasConceptScore W2090768907C150194340 @default.
- W2090768907 hasConceptScore W2090768907C150903083 @default.
- W2090768907 hasConceptScore W2090768907C162853370 @default.
- W2090768907 hasConceptScore W2090768907C165864922 @default.
- W2090768907 hasConceptScore W2090768907C195286587 @default.
- W2090768907 hasConceptScore W2090768907C22744801 @default.
- W2090768907 hasConceptScore W2090768907C2780625559 @default.
- W2090768907 hasConceptScore W2090768907C54355233 @default.
- W2090768907 hasConceptScore W2090768907C70721500 @default.
- W2090768907 hasConceptScore W2090768907C86803240 @default.
- W2090768907 hasIssue "3" @default.
- W2090768907 hasLocation W20907689071 @default.
- W2090768907 hasLocation W20907689072 @default.
- W2090768907 hasOpenAccess W2090768907 @default.
- W2090768907 hasPrimaryLocation W20907689071 @default.
- W2090768907 hasRelatedWork W2034820091 @default.
- W2090768907 hasRelatedWork W2069194230 @default.
- W2090768907 hasRelatedWork W2079987784 @default.
- W2090768907 hasRelatedWork W2088411685 @default.
- W2090768907 hasRelatedWork W2137360360 @default.
- W2090768907 hasRelatedWork W2284195039 @default.
- W2090768907 hasRelatedWork W2413456745 @default.
- W2090768907 hasRelatedWork W2413687222 @default.
- W2090768907 hasRelatedWork W2606105109 @default.
- W2090768907 hasRelatedWork W311012215 @default.
- W2090768907 hasVolume "7" @default.
- W2090768907 isParatext "false" @default.
- W2090768907 isRetracted "false" @default.
- W2090768907 magId "2090768907" @default.
- W2090768907 workType "article" @default.