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- W2090798019 abstract "Phorbol myristate acetate (PMA), a potent activator of Ca2+- and phospholipid-dependent protein kinase (protein kinase C), evoked amylase release from rat parotid cells. In dose-response studies, PMA stimulated amylase release independently of db-cAMP, but potentiated the effect of carbachol. PMA and A23187, a Ca2+ ionophore, synergistically increased amylase release. The maximum effect of carbachol was further enhanced by PMA but not by A23187, suggesting that protein kinase C is not fully activated by the muscarinic-cholinergic agonist under the condition where calcium is fully utilized for amylase secretion." @default.
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- W2090798019 date "1986-04-07" @default.
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- W2090798019 title "Phorbol ester stimulates amylase secretion from rat parotid cells" @default.
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- W2090798019 doi "https://doi.org/10.1016/0014-5793(86)81222-4" @default.
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