Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090811102> ?p ?o ?g. }
- W2090811102 endingPage "107" @default.
- W2090811102 startingPage "99" @default.
- W2090811102 abstract "The aryl hydrocarbon receptor (AhR) mediates a variety of biological responses to ubiquitous environmental pollutants. In this study the effect of administration of β-naphthoflavone (BNF), potent AhR ligand, on the expression of AhR, AhRR, CYP1A1, CYP1A2, CYP1B1, NQO1, GSTA1, ALDH3A1 and UGT1A genes encoding the enzymes controlled by AhR were examined in thirteen laryngeal tumor cell lines and in HepaRG cell line. The analyzed cell lines were derived from patients with squamous laryngeal cancer, with history of cigarette smoking and without signs of human papillomavirus types 16 and 18 infection in investigated cells. Quantitative real-time RT-PCR analysis revealed huge interindividual differences in expression of genes from AhR regulatory network. Our results strongly suggest predominant effect of DNA methylation on induction of CYP1A1 expression by AhR ligands as well. Our results indicate that differentiated HepaRG cell line appeared to be very good substitute for human liver in studies on xenobiotic metabolism by AhR regulated enzymes." @default.
- W2090811102 created "2016-06-24" @default.
- W2090811102 creator A5011519954 @default.
- W2090811102 creator A5016626377 @default.
- W2090811102 creator A5027461031 @default.
- W2090811102 creator A5034339498 @default.
- W2090811102 creator A5048783189 @default.
- W2090811102 creator A5052156144 @default.
- W2090811102 creator A5062991802 @default.
- W2090811102 creator A5064193017 @default.
- W2090811102 creator A5082286365 @default.
- W2090811102 date "2014-11-01" @default.
- W2090811102 modified "2023-10-01" @default.
- W2090811102 title "Diversified expression of aryl hydrocarbon receptor dependent genes in human laryngeal squamous cell carcinoma cell lines treated with β-naphthoflavone" @default.
- W2090811102 cites W1545314652 @default.
- W2090811102 cites W183837874 @default.
- W2090811102 cites W1964232860 @default.
- W2090811102 cites W1968222807 @default.
- W2090811102 cites W1972526611 @default.
- W2090811102 cites W1979889746 @default.
- W2090811102 cites W1980455299 @default.
- W2090811102 cites W1981407146 @default.
- W2090811102 cites W1983298872 @default.
- W2090811102 cites W1988229163 @default.
- W2090811102 cites W2000421237 @default.
- W2090811102 cites W2002396362 @default.
- W2090811102 cites W2005943627 @default.
- W2090811102 cites W2014914547 @default.
- W2090811102 cites W2015829211 @default.
- W2090811102 cites W2016629712 @default.
- W2090811102 cites W2026959257 @default.
- W2090811102 cites W2027254129 @default.
- W2090811102 cites W2027656505 @default.
- W2090811102 cites W2029275372 @default.
- W2090811102 cites W2030607204 @default.
- W2090811102 cites W2031426795 @default.
- W2090811102 cites W2032217767 @default.
- W2090811102 cites W2033888195 @default.
- W2090811102 cites W2040290149 @default.
- W2090811102 cites W2045931107 @default.
- W2090811102 cites W2048300595 @default.
- W2090811102 cites W2048368626 @default.
- W2090811102 cites W2053192498 @default.
- W2090811102 cites W2060732810 @default.
- W2090811102 cites W2062467703 @default.
- W2090811102 cites W2074637575 @default.
- W2090811102 cites W2076547904 @default.
- W2090811102 cites W2094628672 @default.
- W2090811102 cites W2096666806 @default.
- W2090811102 cites W2097989455 @default.
- W2090811102 cites W2101071262 @default.
- W2090811102 cites W2106401558 @default.
- W2090811102 cites W2108836663 @default.
- W2090811102 cites W2122101802 @default.
- W2090811102 cites W2124054636 @default.
- W2090811102 cites W2124739658 @default.
- W2090811102 cites W2138913971 @default.
- W2090811102 cites W2141274038 @default.
- W2090811102 cites W2145525843 @default.
- W2090811102 cites W2163710445 @default.
- W2090811102 doi "https://doi.org/10.1016/j.toxlet.2014.09.005" @default.
- W2090811102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25218365" @default.
- W2090811102 hasPublicationYear "2014" @default.
- W2090811102 type Work @default.
- W2090811102 sameAs 2090811102 @default.
- W2090811102 citedByCount "10" @default.
- W2090811102 countsByYear W20908111022016 @default.
- W2090811102 countsByYear W20908111022017 @default.
- W2090811102 countsByYear W20908111022018 @default.
- W2090811102 countsByYear W20908111022019 @default.
- W2090811102 countsByYear W20908111022022 @default.
- W2090811102 crossrefType "journal-article" @default.
- W2090811102 hasAuthorship W2090811102A5011519954 @default.
- W2090811102 hasAuthorship W2090811102A5016626377 @default.
- W2090811102 hasAuthorship W2090811102A5027461031 @default.
- W2090811102 hasAuthorship W2090811102A5034339498 @default.
- W2090811102 hasAuthorship W2090811102A5048783189 @default.
- W2090811102 hasAuthorship W2090811102A5052156144 @default.
- W2090811102 hasAuthorship W2090811102A5062991802 @default.
- W2090811102 hasAuthorship W2090811102A5064193017 @default.
- W2090811102 hasAuthorship W2090811102A5082286365 @default.
- W2090811102 hasConcept C104317684 @default.
- W2090811102 hasConcept C114246631 @default.
- W2090811102 hasConcept C126322002 @default.
- W2090811102 hasConcept C1491633281 @default.
- W2090811102 hasConcept C150194340 @default.
- W2090811102 hasConcept C155701950 @default.
- W2090811102 hasConcept C165864922 @default.
- W2090811102 hasConcept C170493617 @default.
- W2090811102 hasConcept C181199279 @default.
- W2090811102 hasConcept C190727270 @default.
- W2090811102 hasConcept C2780473477 @default.
- W2090811102 hasConcept C29730261 @default.
- W2090811102 hasConcept C33594762 @default.
- W2090811102 hasConcept C502942594 @default.
- W2090811102 hasConcept C526171541 @default.
- W2090811102 hasConcept C54355233 @default.
- W2090811102 hasConcept C55493867 @default.