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- W2090815821 abstract "The posterodorsal medial amygdala (MePD) exhibits numerous sex differences including differences in volume and in the number and morphology of neurons and astroctyes. In adulthood, gonadal hormones, including both androgens and estrogens, have been shown to play a role in maintaining the masculine character of many of these sex differences, but whether adult gonadal hormones maintain the increased number and complexity of astrocytes in the male MePD was unknown. To answer this question we examined astrocytes in the MePD of male and female Long Evans rats that were gonadectomized as adults and treated for 30 days with either testosterone or a control treatment. At the end of treatment brains were collected and immunostained for glial fibrillary acidic protein. Stereological analysis revealed that adult androgen levels influenced the number and complexity of astrocytes in the MePD of both sexes, but the specific effects of androgens were different in males and females. However, sex differences in the number and complexity of adult astrocytes persisted even in the absence of gonadal hormones in adulthood, suggesting that androgens also act earlier in life to determine these adult sex differences. Using immunofluorescence and confocal microscopy, we found robust androgen receptor immunostaining in a subpopulation of MePD astrocytes, suggesting that testosterone may act directly on MePD astrocytes to influence their structure and function." @default.
- W2090815821 created "2016-06-24" @default.
- W2090815821 creator A5011976319 @default.
- W2090815821 creator A5017882182 @default.
- W2090815821 creator A5054737356 @default.
- W2090815821 creator A5064546194 @default.
- W2090815821 creator A5071313567 @default.
- W2090815821 date "2012-05-14" @default.
- W2090815821 modified "2023-10-17" @default.
- W2090815821 title "Astrocytes in the rat medial amygdala are responsive to adult androgens" @default.
- W2090815821 cites W1489710030 @default.
- W2090815821 cites W1550159293 @default.
- W2090815821 cites W1564190433 @default.
- W2090815821 cites W1703928766 @default.
- W2090815821 cites W1725779997 @default.
- W2090815821 cites W1893559159 @default.
- W2090815821 cites W1965317564 @default.
- W2090815821 cites W1968315786 @default.
- W2090815821 cites W1971276070 @default.
- W2090815821 cites W1974695866 @default.
- W2090815821 cites W1984181330 @default.
- W2090815821 cites W1985943544 @default.
- W2090815821 cites W1987163246 @default.
- W2090815821 cites W1988101363 @default.
- W2090815821 cites W1989691108 @default.
- W2090815821 cites W1989826158 @default.
- W2090815821 cites W1991172664 @default.
- W2090815821 cites W1992650105 @default.
- W2090815821 cites W1994584537 @default.
- W2090815821 cites W1996603253 @default.
- W2090815821 cites W2000193264 @default.
- W2090815821 cites W2002190655 @default.
- W2090815821 cites W2003885801 @default.
- W2090815821 cites W2004745897 @default.
- W2090815821 cites W2005531807 @default.
- W2090815821 cites W2006268333 @default.
- W2090815821 cites W2006837976 @default.
- W2090815821 cites W2007801101 @default.
- W2090815821 cites W2009986139 @default.
- W2090815821 cites W2011050538 @default.
- W2090815821 cites W2011595502 @default.
- W2090815821 cites W2012578231 @default.
- W2090815821 cites W2013605854 @default.
- W2090815821 cites W2014596933 @default.
- W2090815821 cites W2017154435 @default.
- W2090815821 cites W2018381563 @default.
- W2090815821 cites W2021828255 @default.
- W2090815821 cites W2023065478 @default.
- W2090815821 cites W2023500766 @default.
- W2090815821 cites W2025742118 @default.
- W2090815821 cites W2031611126 @default.
- W2090815821 cites W2032225883 @default.
- W2090815821 cites W2032888140 @default.
- W2090815821 cites W2035843983 @default.
- W2090815821 cites W2036872212 @default.
- W2090815821 cites W2039615307 @default.
- W2090815821 cites W2039809166 @default.
- W2090815821 cites W2042179361 @default.
- W2090815821 cites W2048158461 @default.
- W2090815821 cites W2048856370 @default.
- W2090815821 cites W2050581082 @default.
- W2090815821 cites W2051391913 @default.
- W2090815821 cites W2054110130 @default.
- W2090815821 cites W2060334997 @default.
- W2090815821 cites W2060506544 @default.
- W2090815821 cites W2062642133 @default.
- W2090815821 cites W2063515122 @default.
- W2090815821 cites W2069203742 @default.
- W2090815821 cites W2080957084 @default.
- W2090815821 cites W2084216483 @default.
- W2090815821 cites W2088553314 @default.
- W2090815821 cites W2089338980 @default.
- W2090815821 cites W2090219097 @default.
- W2090815821 cites W2092355605 @default.
- W2090815821 cites W2094755254 @default.
- W2090815821 cites W2095827218 @default.
- W2090815821 cites W2099316702 @default.
- W2090815821 cites W2104235622 @default.
- W2090815821 cites W2106720796 @default.
- W2090815821 cites W2108865171 @default.
- W2090815821 cites W2110339714 @default.
- W2090815821 cites W2115698612 @default.
- W2090815821 cites W2116716261 @default.
- W2090815821 cites W2123095717 @default.
- W2090815821 cites W2125607337 @default.
- W2090815821 cites W2129567809 @default.
- W2090815821 cites W2129837792 @default.
- W2090815821 cites W2142448948 @default.
- W2090815821 cites W2146362285 @default.
- W2090815821 cites W2150082728 @default.
- W2090815821 cites W2156986289 @default.
- W2090815821 cites W2161218552 @default.
- W2090815821 cites W2164729229 @default.
- W2090815821 cites W2169564449 @default.
- W2090815821 cites W4234869015 @default.
- W2090815821 cites W4240260187 @default.
- W2090815821 cites W4244877063 @default.
- W2090815821 cites W4255396331 @default.