Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090828757> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2090828757 endingPage "1162" @default.
- W2090828757 startingPage "1159" @default.
- W2090828757 abstract "Halothane and other halogenated anesthetic agents are liquids which are highly soluble in rubber and plastic materials widely used as components of anesthesia machines. These agents must be administered using machines equipped with vaporizers. We report a patient with a past history of halothane hepatitis in whom recurrence was suspected despite the fact that halothane had been avoided purposely during the subsequent operation. Circumstances led us to believe that inapparent circuit contamination of vaporizer-equipped anesthesia machine with halothane may be responsible for the inadvertant rechallenge and recurrence of halothane hepatitis. Vaporizer-equipped machines were tested for inapparent contamination with halothane and enflurane using Perkin-Elmer mass spectrometer. Oxygen alone was passed through the anesthesia circuits, and gas in the efferent limbs of the machines was tested for halothane (in eight machines) and enflurane (in two machines) which were found in various concentrations in all machines so tested. Our findings suggest that inapparent contamination may be widely prevalent in vaporizer-equipped anesthesia machines. The validity of this conclusion was confirmed in five patients with previous diagnosis of halothane hepatitis who subsequently underwent operations under general anesthesia during which machines never equipped with vaporizers were successful in preventing recurrence of hepatitis. We conclude that patients with a prior history of halothane hepatitis are at risk of inapparent circuit contamination-induced recurrent hepatitis. Unless such contamination can be confidently excluded, vaporizer-equipped machines should not be used to administer general anesthesia in these susceptible patients." @default.
- W2090828757 created "2016-06-24" @default.
- W2090828757 creator A5002255968 @default.
- W2090828757 creator A5088896817 @default.
- W2090828757 creator A5089885026 @default.
- W2090828757 date "1985-11-01" @default.
- W2090828757 modified "2023-09-25" @default.
- W2090828757 title "Halothane hepatitis without halothane: Role of inapparent circuit contamination and its prevention" @default.
- W2090828757 cites W2028015545 @default.
- W2090828757 cites W2029589569 @default.
- W2090828757 cites W2031636363 @default.
- W2090828757 cites W2036603880 @default.
- W2090828757 cites W2036764931 @default.
- W2090828757 cites W2048763356 @default.
- W2090828757 cites W2079689801 @default.
- W2090828757 cites W2085741321 @default.
- W2090828757 cites W2163211226 @default.
- W2090828757 cites W4244531608 @default.
- W2090828757 doi "https://doi.org/10.1002/hep.1840050616" @default.
- W2090828757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4065821" @default.
- W2090828757 hasPublicationYear "1985" @default.
- W2090828757 type Work @default.
- W2090828757 sameAs 2090828757 @default.
- W2090828757 citedByCount "17" @default.
- W2090828757 countsByYear W20908287572012 @default.
- W2090828757 countsByYear W20908287572013 @default.
- W2090828757 countsByYear W20908287572018 @default.
- W2090828757 crossrefType "journal-article" @default.
- W2090828757 hasAuthorship W2090828757A5002255968 @default.
- W2090828757 hasAuthorship W2090828757A5088896817 @default.
- W2090828757 hasAuthorship W2090828757A5089885026 @default.
- W2090828757 hasConcept C112570922 @default.
- W2090828757 hasConcept C142724271 @default.
- W2090828757 hasConcept C18903297 @default.
- W2090828757 hasConcept C2776932660 @default.
- W2090828757 hasConcept C2777858289 @default.
- W2090828757 hasConcept C2778162923 @default.
- W2090828757 hasConcept C2781208240 @default.
- W2090828757 hasConcept C2908650173 @default.
- W2090828757 hasConcept C42219234 @default.
- W2090828757 hasConcept C71924100 @default.
- W2090828757 hasConcept C86803240 @default.
- W2090828757 hasConceptScore W2090828757C112570922 @default.
- W2090828757 hasConceptScore W2090828757C142724271 @default.
- W2090828757 hasConceptScore W2090828757C18903297 @default.
- W2090828757 hasConceptScore W2090828757C2776932660 @default.
- W2090828757 hasConceptScore W2090828757C2777858289 @default.
- W2090828757 hasConceptScore W2090828757C2778162923 @default.
- W2090828757 hasConceptScore W2090828757C2781208240 @default.
- W2090828757 hasConceptScore W2090828757C2908650173 @default.
- W2090828757 hasConceptScore W2090828757C42219234 @default.
- W2090828757 hasConceptScore W2090828757C71924100 @default.
- W2090828757 hasConceptScore W2090828757C86803240 @default.
- W2090828757 hasIssue "6" @default.
- W2090828757 hasLocation W20908287571 @default.
- W2090828757 hasLocation W20908287572 @default.
- W2090828757 hasOpenAccess W2090828757 @default.
- W2090828757 hasPrimaryLocation W20908287571 @default.
- W2090828757 hasRelatedWork W1968026702 @default.
- W2090828757 hasRelatedWork W1988980343 @default.
- W2090828757 hasRelatedWork W2036201607 @default.
- W2090828757 hasRelatedWork W2091409264 @default.
- W2090828757 hasRelatedWork W21811491 @default.
- W2090828757 hasRelatedWork W2401802050 @default.
- W2090828757 hasRelatedWork W2411480200 @default.
- W2090828757 hasRelatedWork W2413317235 @default.
- W2090828757 hasRelatedWork W2466371232 @default.
- W2090828757 hasRelatedWork W2490145494 @default.
- W2090828757 hasVolume "5" @default.
- W2090828757 isParatext "false" @default.
- W2090828757 isRetracted "false" @default.
- W2090828757 magId "2090828757" @default.
- W2090828757 workType "article" @default.