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- W2090831367 abstract "Cold supernatant which was prepared from factor VIII:C containing cryoprecipitate was seeded with HIV-1, then treated with a mixture of tri (n-butyl) phosphate (TNBP) and triton X-100. A greater than 10(11)-fold reduction of HIV-1 infectivity was observed. In a separate experiment, cold supernatant which had been seeded with HIV-1 was chromatographed on an immunoaffinity column, resulting in a 10(4)-fold reduction of infectivity. None of the 17 patients treated with the purified product and followed for at least three months has shown serologic evidence of HIV-1 or other viral infections." @default.
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- W2090831367 date "1989-09-01" @default.
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- W2090831367 title "Inactivation and removal of human immunodeficiency virus in monoclonal purified antihemophilic factor (human) (hemofil®m)" @default.
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- W2090831367 doi "https://doi.org/10.1016/0049-3848(89)90395-2" @default.
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