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- W2090836669 abstract "The in vitro activity of an immunotoxin (IT) prepared by conjugating the monocyte specific RoMo-1 monoclonal antibody and partially inactivated Mistletoe lectin I (dMLI) containing inactivated B chain has been initially characterized. It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations. Therefore it seems to be possible to use this non-sugar binding holotoxin for immunotoxin preparation." @default.
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- W2090836669 date "1989-01-01" @default.
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- W2090836669 title "Selective killing of human monocytes by an immunotoxin containing partially denatured mistletoe lectin I" @default.
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- W2090836669 doi "https://doi.org/10.1016/0192-0561(89)90121-5" @default.
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