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- W2090848123 abstract "Abstract The effects of carbachol perfusion in the pontine (PRF) and mesencephalic (MRF) reticular formation on contiguous multiple-unit activity (MUA) and other sleep-waking parameters of cats were determined. Perfusion of carbachol into the PRF significantly increased the number of contiguous MUA neuronal spikes. There was a linear relationship between the number of minutes of perfusion and MUA neuronal spikes from the 1st to the 8th minute (estimated 1 to 8 μg), followed by a plateau of maximal MUA activation from the 8th to the 10th minute (estimated 8 to 10 μg), and a subsequent decrease in number of MUA cellular spikes from the 10th to the 11th minute (estimated 10 to 11μg) when the perfusion was discontinued. Concomitantly, the perfusion significantly decreased electromyographic MUA (hypotonia) but it did not systematically modify the mesencephalic reticular formation and other electrophysiologic and behavioral sleep-waking parameters. Perfusion of carbachol into the MRF significantly increased the number of contiguous MUA neuronal spikes. There was a linear relationship between the number of minutes of perfusion and the number of MUA neuronal spikes from the 1st to the 11th minute (estimated 1 to 11 μg) when the perfusion was discontinued. Concomitantly, the perfusion significantly increased electromyographic MUA (hypertonia) and produced a systematic electrophysiologic and behavioral arousal response." @default.
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- W2090848123 date "1981-05-01" @default.
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- W2090848123 title "Carbachol “push-pull” perfusion in the reticular formation: Effect on the contiguous multiple-unit activity and other sleep-waking parameters in cats" @default.
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- W2090848123 doi "https://doi.org/10.1016/0014-4886(81)90226-0" @default.
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