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- W2090853731 abstract "Invertebrate troponin C typically contains Ca2+-specific binding sites, sites II and IV, in the N- and C-terminal domains, respectively. To investigate the roles of these sites for Ca2+-dependent regulation of muscle contraction, we generated lobster troponin C mutants, and analyzed their Ca2+-binding properties and regulatory effects on actomyosin–tropomyosin Mg-ATPase activity. The results suggest that Ca2+ binding to site IV is responsible for regulation at relatively low Ca2+ concentrations, while site II has an essential role in full activation at higher Ca2+ concentrations." @default.
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- W2090853731 date "2013-07-03" @default.
- W2090853731 modified "2023-10-18" @default.
- W2090853731 title "Ca<sup>2+</sup>-binding properties and regulatory roles of lobster troponin C sites II and IV" @default.
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- W2090853731 doi "https://doi.org/10.1016/j.febslet.2013.06.042" @default.
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