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- W2090858309 abstract "MULTIPLE sclerosis was recognized as a clinical entity early in the nineteenth century by Charcot. Since then its pathology and clinical symptomatology have been defined, but the etiology of this disease still remains an enigma. It has been ascribed to many and varied causes — among them, infectious agents, toxins, vitamin deficiencies, congenital and hereditary phenomena and allergic and biochemical reactions.1 , 2 Buzzard3 (1911), on the basis of the resemblance between multiple sclerosis and cerebrospinal syphilis, postulated that a treponema is the responsible organism in multiple sclerosis. A few years later, Kuhn and Steiner4 claimed to have isolated a spiral organism . . ." @default.
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- W2090858309 date "1962-05-24" @default.
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- W2090858309 title "Attempted Cultivation of Spirochaeta Myelophthora and a Test of the Validity of the Complement-Fixation Test in Multiple Sclerosis" @default.
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- W2090858309 doi "https://doi.org/10.1056/nejm196205242662104" @default.
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