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- W2090866245 abstract "While numerous studies of aldosterone 18-glucuronide excretion in pregnancy have been published few data have been available about the other major catabolite of aldosterone, the 3α,5β-tetrahydro derivative. Tetrahydroaldosterone, measured by gas Chromatographie techniques, is higher in the luteal phase than in the follicular phase of nonpregnant young women. A wide range in tetrahydroaldosterone excretion was noted in pregnant subjects on unrestricted salt intake at the same stage of gestation. While some values remained at those levels encountered during the menstrual cycle, even in the last trimester of pregnancy, the average excretion generally rose with added weeks of gestation. The increases in tetrahydroaldosterone excretion are smaller than those reported by other workers for the 8-glucuronide aldosterone metabolite, supporting the suggestion made by K. M. Jones, R. Lloyd-Jones, A. Riondel, J. F. Tait, S. A. S. Tait, R. D. Bulbrook and F.C. Greenwood (Acta Endocrinol., 30 (1959) 321), as well as by J.F. Tait and B. Little (J. Clin. Invest., 47 (1968) 2423), that aldosterone metabolism is altered in pregnancy." @default.
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- W2090866245 date "1973-05-01" @default.
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- W2090866245 title "Excretion of tetrahydroaldosterone in normal pregnancy" @default.
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- W2090866245 doi "https://doi.org/10.1016/0009-8981(73)90442-7" @default.
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