Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090867938> ?p ?o ?g. }
- W2090867938 endingPage "142" @default.
- W2090867938 startingPage "136" @default.
- W2090867938 abstract "Regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non-self-antigens, thus playing critical roles in preventing autoimmune diseases. However, tumor cells may take advantage of Treg cells to protect themselves from immune attack elicited by vaccines. Recent studies demonstrate the presence of Treg cells in various types of cancers and their suppressive function. Therefore, Treg cells at tumor sites have detrimental effects on immunotherapy directed to cancer and infectious diseases. This review will discuss antigen specificity of Treg cells, the factors that contribute to Treg cell generation and suppressive function, and their regulation through Toll-like receptor signaling. It was generally though that TLR-mediated recognition of specific structures of invading pathogens initiate innate as well as adaptive immune responses through dendritic cells. New evidence suggests that TLR signaling may directly regulate the suppressive function of Treg cells. Linking TLR signaling to the functional control of Treg cells opens intriguing opportunities to shift the balance between CD4(+) T-helper and Treg cells, in ways that may improve the outcome of cancer immunotherapy." @default.
- W2090867938 created "2016-06-24" @default.
- W2090867938 creator A5053227341 @default.
- W2090867938 creator A5070717343 @default.
- W2090867938 creator A5089144939 @default.
- W2090867938 date "2006-04-01" @default.
- W2090867938 modified "2023-10-16" @default.
- W2090867938 title "Regulatory T cells and Toll-like receptors in tumor immunity" @default.
- W2090867938 cites W1503997891 @default.
- W2090867938 cites W1521212256 @default.
- W2090867938 cites W1522368306 @default.
- W2090867938 cites W1530044612 @default.
- W2090867938 cites W1530782041 @default.
- W2090867938 cites W1577612079 @default.
- W2090867938 cites W1591572654 @default.
- W2090867938 cites W1966129458 @default.
- W2090867938 cites W1969072247 @default.
- W2090867938 cites W1972776583 @default.
- W2090867938 cites W1974692207 @default.
- W2090867938 cites W1984393957 @default.
- W2090867938 cites W1985482500 @default.
- W2090867938 cites W1990227965 @default.
- W2090867938 cites W1990555839 @default.
- W2090867938 cites W1991236592 @default.
- W2090867938 cites W1991287153 @default.
- W2090867938 cites W1992699637 @default.
- W2090867938 cites W1994391392 @default.
- W2090867938 cites W1995570137 @default.
- W2090867938 cites W2001740313 @default.
- W2090867938 cites W2002726823 @default.
- W2090867938 cites W2003257616 @default.
- W2090867938 cites W2004465286 @default.
- W2090867938 cites W2004708987 @default.
- W2090867938 cites W2011678998 @default.
- W2090867938 cites W2013548919 @default.
- W2090867938 cites W2017217637 @default.
- W2090867938 cites W2021603971 @default.
- W2090867938 cites W2024351056 @default.
- W2090867938 cites W2026942934 @default.
- W2090867938 cites W2027415000 @default.
- W2090867938 cites W2028282358 @default.
- W2090867938 cites W2033415145 @default.
- W2090867938 cites W2045948025 @default.
- W2090867938 cites W2047203592 @default.
- W2090867938 cites W2052521175 @default.
- W2090867938 cites W2056102876 @default.
- W2090867938 cites W2067164351 @default.
- W2090867938 cites W2067648924 @default.
- W2090867938 cites W2076819781 @default.
- W2090867938 cites W2085542638 @default.
- W2090867938 cites W2090640877 @default.
- W2090867938 cites W2096696255 @default.
- W2090867938 cites W2097074641 @default.
- W2090867938 cites W2097811455 @default.
- W2090867938 cites W2103990111 @default.
- W2090867938 cites W2106187671 @default.
- W2090867938 cites W2110753254 @default.
- W2090867938 cites W2115241901 @default.
- W2090867938 cites W2116201625 @default.
- W2090867938 cites W2117614250 @default.
- W2090867938 cites W2119939110 @default.
- W2090867938 cites W2121626779 @default.
- W2090867938 cites W2123677383 @default.
- W2090867938 cites W2128595912 @default.
- W2090867938 cites W2129127258 @default.
- W2090867938 cites W2129767277 @default.
- W2090867938 cites W2130486201 @default.
- W2090867938 cites W2130520731 @default.
- W2090867938 cites W2132427916 @default.
- W2090867938 cites W2137467818 @default.
- W2090867938 cites W2141785549 @default.
- W2090867938 cites W2145312523 @default.
- W2090867938 cites W2146934919 @default.
- W2090867938 cites W2148911309 @default.
- W2090867938 cites W2149123553 @default.
- W2090867938 cites W2150453791 @default.
- W2090867938 cites W2150678612 @default.
- W2090867938 cites W2151246207 @default.
- W2090867938 cites W2152432411 @default.
- W2090867938 cites W2156592930 @default.
- W2090867938 cites W2157339124 @default.
- W2090867938 cites W2158606911 @default.
- W2090867938 cites W2159987448 @default.
- W2090867938 cites W2160117150 @default.
- W2090867938 cites W2161208630 @default.
- W2090867938 cites W2162819001 @default.
- W2090867938 cites W2165591553 @default.
- W2090867938 cites W2168491130 @default.
- W2090867938 cites W2792966232 @default.
- W2090867938 cites W4238210500 @default.
- W2090867938 doi "https://doi.org/10.1016/j.smim.2006.01.008" @default.
- W2090867938 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16469504" @default.
- W2090867938 hasPublicationYear "2006" @default.
- W2090867938 type Work @default.
- W2090867938 sameAs 2090867938 @default.
- W2090867938 citedByCount "52" @default.
- W2090867938 countsByYear W20908679382012 @default.
- W2090867938 countsByYear W20908679382013 @default.