Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090870981> ?p ?o ?g. }
- W2090870981 endingPage "2142" @default.
- W2090870981 startingPage "2123" @default.
- W2090870981 abstract "Cortical and subcortical inputs to the striatum are functionally highly organized and they obey to some extent striatal patch-matrix topography. Whether this organization is reflected in the density of various glutamatergic endings is unknown. We therefore mapped boutons expressing the vesicular glutamate transporters VGluT1 and VGluT2, together with boutons immunoreactive for vesicular γ-aminobutyric acid (GABA) transporter (VGAT) in patch and matrix throughout the striatum. We used triple-immunofluorescence staining followed by multichannel, high-magnification confocal laser scanning and 3D object recognition. Densities of VGluT1 and VGluT2 boutons were on average higher in matrix than in patches in all striatal sectors. The dorsal one-third of the striatum contained the highest densities of VGluT1 boutons. Subsequent 3D surface plotting revealed patterns of density “valleys” in the dorsomedial striatum coinciding with patch locations in the patch-matrix mapping. The density of VGluT1 boutons increased along three axes: ventrolateral-to-dorsomedial, ventral-to-dorsal, and lateral-to-medial. In contrast, VGluT2 showed a global increase in density from lateral to medial and a relatively high density in the ventral striatum. VGAT appeared more evenly distributed in the striatal patch-matrix than the VGluTs, with a tendency of bouton density to increase from medial to lateral. We noted a good correlation between the high VGluT1 bouton density dorsomedially with inputs from dorsal medial prefrontal cortex and related thalamic regions, and the enhanced VGluT2 input ventromedially with input from ventral medial prefrontal cortex and thalamic, amygdaloid, and hippocampal sources. J. Comp. Neurol. 520:2123–2142, 2012. © 2011 Wiley Periodicals, Inc." @default.
- W2090870981 created "2016-06-24" @default.
- W2090870981 creator A5025806011 @default.
- W2090870981 creator A5064363817 @default.
- W2090870981 creator A5074781107 @default.
- W2090870981 creator A5078593206 @default.
- W2090870981 date "2012-04-12" @default.
- W2090870981 modified "2023-09-23" @default.
- W2090870981 title "Density gradients of vesicular glutamate- and GABA transporter-immunoreactive boutons in calbindin- and μ-opioid receptor-defined compartments in the rat striatum" @default.
- W2090870981 cites W1505732106 @default.
- W2090870981 cites W1575810634 @default.
- W2090870981 cites W1591789321 @default.
- W2090870981 cites W1788084167 @default.
- W2090870981 cites W1825807651 @default.
- W2090870981 cites W1925686653 @default.
- W2090870981 cites W1964240411 @default.
- W2090870981 cites W1968353095 @default.
- W2090870981 cites W1976963429 @default.
- W2090870981 cites W1978803337 @default.
- W2090870981 cites W1988829918 @default.
- W2090870981 cites W1992587213 @default.
- W2090870981 cites W1995510156 @default.
- W2090870981 cites W1996535168 @default.
- W2090870981 cites W1998722012 @default.
- W2090870981 cites W2001323697 @default.
- W2090870981 cites W2002343527 @default.
- W2090870981 cites W2015659804 @default.
- W2090870981 cites W2017165713 @default.
- W2090870981 cites W2018576843 @default.
- W2090870981 cites W2021158519 @default.
- W2090870981 cites W2022916469 @default.
- W2090870981 cites W2025633802 @default.
- W2090870981 cites W2026547228 @default.
- W2090870981 cites W2028474222 @default.
- W2090870981 cites W2032471499 @default.
- W2090870981 cites W2041382770 @default.
- W2090870981 cites W2042369174 @default.
- W2090870981 cites W2043207588 @default.
- W2090870981 cites W2046743188 @default.
- W2090870981 cites W2047100271 @default.
- W2090870981 cites W2050123488 @default.
- W2090870981 cites W2056886931 @default.
- W2090870981 cites W2057787317 @default.
- W2090870981 cites W2069209764 @default.
- W2090870981 cites W2071132127 @default.
- W2090870981 cites W2080093812 @default.
- W2090870981 cites W2086884518 @default.
- W2090870981 cites W2088415801 @default.
- W2090870981 cites W2094255560 @default.
- W2090870981 cites W2094973127 @default.
- W2090870981 cites W2096488993 @default.
- W2090870981 cites W2099546976 @default.
- W2090870981 cites W2104311488 @default.
- W2090870981 cites W2110705999 @default.
- W2090870981 cites W2123576957 @default.
- W2090870981 cites W2124733101 @default.
- W2090870981 cites W2137422526 @default.
- W2090870981 cites W2138788043 @default.
- W2090870981 cites W2138854550 @default.
- W2090870981 cites W2149921519 @default.
- W2090870981 cites W2158776928 @default.
- W2090870981 cites W2160501333 @default.
- W2090870981 cites W2164237857 @default.
- W2090870981 cites W2165831708 @default.
- W2090870981 cites W3023504226 @default.
- W2090870981 cites W93745480 @default.
- W2090870981 doi "https://doi.org/10.1002/cne.23031" @default.
- W2090870981 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22173881" @default.
- W2090870981 hasPublicationYear "2012" @default.
- W2090870981 type Work @default.
- W2090870981 sameAs 2090870981 @default.
- W2090870981 citedByCount "18" @default.
- W2090870981 countsByYear W20908709812012 @default.
- W2090870981 countsByYear W20908709812013 @default.
- W2090870981 countsByYear W20908709812014 @default.
- W2090870981 countsByYear W20908709812015 @default.
- W2090870981 countsByYear W20908709812016 @default.
- W2090870981 countsByYear W20908709812018 @default.
- W2090870981 countsByYear W20908709812019 @default.
- W2090870981 countsByYear W20908709812021 @default.
- W2090870981 crossrefType "journal-article" @default.
- W2090870981 hasAuthorship W2090870981A5025806011 @default.
- W2090870981 hasAuthorship W2090870981A5064363817 @default.
- W2090870981 hasAuthorship W2090870981A5074781107 @default.
- W2090870981 hasAuthorship W2090870981A5078593206 @default.
- W2090870981 hasConcept C105702510 @default.
- W2090870981 hasConcept C148762608 @default.
- W2090870981 hasConcept C169760540 @default.
- W2090870981 hasConcept C170493617 @default.
- W2090870981 hasConcept C2776743251 @default.
- W2090870981 hasConcept C2780062018 @default.
- W2090870981 hasConcept C2780648746 @default.
- W2090870981 hasConcept C513476851 @default.
- W2090870981 hasConcept C55493867 @default.
- W2090870981 hasConcept C61174792 @default.
- W2090870981 hasConcept C86803240 @default.
- W2090870981 hasConceptScore W2090870981C105702510 @default.
- W2090870981 hasConceptScore W2090870981C148762608 @default.