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- W2090874622 abstract "In the majority of resting human peripheral T lymphocytes obtained from separate individuals cytochalasin B (CB) and D (CD) cause a disappearance of microvilli and induce a rapid formation of prominent sac and bleb-like projections with a length of 1-10 microns randomly distributed over the cell surface. During mitogen stimulation the cells lose the tendency to develop such projections when subsequently exposed to CB and CD. By contrast, in activated T lymphocytes the cytochalasins provoke an asymmetric localization of microvilli including cell surface antigens and actin to a prominent protuberance often separated from the cell body by a constriction. This protuberance is distinct from conventional spontaneous uropods formed by conA-stimulated lymphocytes in relation to contact with other cells and with non-cellular surfaces. The cytochalasins therefore in their action distinguish resting small lymphocytes from activated T-cell blasts." @default.
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- W2090874622 date "1983-04-01" @default.
- W2090874622 modified "2023-10-16" @default.
- W2090874622 title "Cytochalasins distinguish by their action resting human T lymphocytes from activated T-cell blasts*1" @default.
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- W2090874622 doi "https://doi.org/10.1016/0014-4827(83)90423-8" @default.
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