FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090879904> ?p ?o ?g. }

• W2090879904 endingPage "1029" @default.
• W2090879904 startingPage "1022" @default.
• W2090879904 abstract "The histological extent of inflammatory bowel disease (IBD) is greater than that evident by colonoscopic evaluation. We hypothesized that metabolic profile in macroscopically un-involved colonic mucosa in IBD is similar to that of controls with healthy colon. We thus assessed the differences in metabolic profile in macroscopically involved and un-involved colonic mucosa of IBD patients to further substantiate the extent of disease. Colonic mucosal biopsies were obtained and snap frozen from both the macroscopically un-involved and involved colonic mucosa of IBD patients and macroscopically normal colonic mucosa of controls and were subjected to in-vitro high-resolution proton (1H) magnetic resonance (MR) spectroscopy and the concentrations of metabolites were determined. Thirty-two metabolites were assigned in the proton MR spectrum of colonic mucosa of IBD patients. The concentrations of amino acids (isoleucine, leucine, valine, arginine, lysine, glutamine/glutamate, alanine), membrane metabolites (choline, glycerophosphorylcholine/phosphorylcholine), glycolytic product (lactate) and short chain fatty acid (formate) were significantly lower while significantly high level of glucose were observed in the macroscopically un-involved colonic mucosa of IBD patients compared to the macroscopically normal mucosa of controls. There was no significant difference in the concentrations of metabolites in macroscopically involved and un-involved colonic mucosa of IBD patients. The metabolic profile in macroscopically un-involved colonic mucosa of IBD patients is similar to that of macroscopically involved mucosa but different from colonic mucosa of controls. This suggests that even macroscopically un-involved colonic mucosa is metabolically abnormal and may explain the increase in extent of disease with time." @default.
• W2090879904 created "2016-06-24" @default.
• W2090879904 creator A5015636922 @default.
• W2090879904 creator A5016928431 @default.
• W2090879904 creator A5025173068 @default.
• W2090879904 creator A5059852221 @default.
• W2090879904 creator A5081437997 @default.
• W2090879904 date "2010-09-01" @default.
• W2090879904 modified "2023-10-16" @default.
• W2090879904 title "Similarity in the metabolic profile in macroscopically involved and un-involved colonic mucosa in patients with inflammatory bowel disease: an in vitro proton (1H) MR spectroscopy study" @default.
• W2090879904 cites W1506819190 @default.
• W2090879904 cites W1612925887 @default.
• W2090879904 cites W1910910895 @default.
• W2090879904 cites W1968633234 @default.
• W2090879904 cites W1971672202 @default.
• W2090879904 cites W1979948289 @default.
• W2090879904 cites W1981193852 @default.
• W2090879904 cites W2000778831 @default.
• W2090879904 cites W2021461643 @default.
• W2090879904 cites W2033560257 @default.
• W2090879904 cites W2053897247 @default.
• W2090879904 cites W2054186211 @default.
• W2090879904 cites W2063380767 @default.
• W2090879904 cites W2067478712 @default.
• W2090879904 cites W2089560557 @default.
• W2090879904 cites W2090201519 @default.
• W2090879904 cites W2097733438 @default.
• W2090879904 cites W2098209207 @default.
• W2090879904 cites W2100438777 @default.
• W2090879904 cites W2101604689 @default.
• W2090879904 cites W2101895513 @default.
• W2090879904 cites W2130382164 @default.
• W2090879904 cites W2137898985 @default.
• W2090879904 cites W2139232831 @default.
• W2090879904 cites W2145819863 @default.
• W2090879904 cites W2165968800 @default.
• W2090879904 cites W2171789845 @default.
• W2090879904 cites W2188248802 @default.
• W2090879904 cites W2291116084 @default.
• W2090879904 cites W2326201219 @default.
• W2090879904 cites W2614197161 @default.
• W2090879904 cites W3149527659 @default.
• W2090879904 doi "https://doi.org/10.1016/j.mri.2010.03.039" @default.
• W2090879904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20418044" @default.
• W2090879904 hasPublicationYear "2010" @default.
• W2090879904 type Work @default.
• W2090879904 sameAs 2090879904 @default.
• W2090879904 citedByCount "38" @default.
• W2090879904 countsByYear W20908799042012 @default.
• W2090879904 countsByYear W20908799042013 @default.
• W2090879904 countsByYear W20908799042014 @default.
• W2090879904 countsByYear W20908799042015 @default.
• W2090879904 countsByYear W20908799042016 @default.
• W2090879904 countsByYear W20908799042018 @default.
• W2090879904 countsByYear W20908799042019 @default.
• W2090879904 countsByYear W20908799042020 @default.
• W2090879904 countsByYear W20908799042021 @default.
• W2090879904 countsByYear W20908799042022 @default.
• W2090879904 crossrefType "journal-article" @default.
• W2090879904 hasAuthorship W2090879904A5015636922 @default.
• W2090879904 hasAuthorship W2090879904A5016928431 @default.
• W2090879904 hasAuthorship W2090879904A5025173068 @default.
• W2090879904 hasAuthorship W2090879904A5059852221 @default.
• W2090879904 hasAuthorship W2090879904A5081437997 @default.
• W2090879904 hasConcept C126322002 @default.
• W2090879904 hasConcept C135870905 @default.
• W2090879904 hasConcept C142724271 @default.
• W2090879904 hasConcept C185592680 @default.
• W2090879904 hasConcept C2777477808 @default.
• W2090879904 hasConcept C2778260677 @default.
• W2090879904 hasConcept C2779134260 @default.
• W2090879904 hasConcept C2779349466 @default.
• W2090879904 hasConcept C2780479503 @default.
• W2090879904 hasConcept C3019368612 @default.
• W2090879904 hasConcept C515207424 @default.
• W2090879904 hasConcept C55493867 @default.
• W2090879904 hasConcept C71924100 @default.
• W2090879904 hasConcept C90924648 @default.
• W2090879904 hasConceptScore W2090879904C126322002 @default.
• W2090879904 hasConceptScore W2090879904C135870905 @default.
• W2090879904 hasConceptScore W2090879904C142724271 @default.
• W2090879904 hasConceptScore W2090879904C185592680 @default.
• W2090879904 hasConceptScore W2090879904C2777477808 @default.
• W2090879904 hasConceptScore W2090879904C2778260677 @default.
• W2090879904 hasConceptScore W2090879904C2779134260 @default.
• W2090879904 hasConceptScore W2090879904C2779349466 @default.
• W2090879904 hasConceptScore W2090879904C2780479503 @default.
• W2090879904 hasConceptScore W2090879904C3019368612 @default.
• W2090879904 hasConceptScore W2090879904C515207424 @default.
• W2090879904 hasConceptScore W2090879904C55493867 @default.
• W2090879904 hasConceptScore W2090879904C71924100 @default.
• W2090879904 hasConceptScore W2090879904C90924648 @default.
• W2090879904 hasIssue "7" @default.
• W2090879904 hasLocation W20908799041 @default.
• W2090879904 hasLocation W20908799042 @default.
• W2090879904 hasOpenAccess W2090879904 @default.
• W2090879904 hasPrimaryLocation W20908799041 @default.
• W2090879904 hasRelatedWork W1505547912 @default.

• next