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- W2090898258 abstract "The normal attachment of sea urchin egg cortical granules to the overlying plasma membrane can be disrupted by urethane, the tertiary amines procaine and tetracaine, and ammonia. Following such treatment, and contrary to the normal situation in mature eggs, the cortical granules can be dislodged from the egg cortex by centrifugal force. In some experiments, procaine treatment alone can disrupt cortical granule attachment enough to prevent exocytosis at fertilization. In such eggs, cortical granules can then be seen in the blastomeres. These observations suggest that a special attachment exists between the cortical granules and the plasma membrane and that if this attachment is sufficiently disrupted, cortical granule exocytosis is prevented. A new technique for the isolation of cortical granules has been developed based on the urethane sensitivity of their attachment to the plasma membrane." @default.
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- W2090898258 title "The effect of local anesthetics and ammonia on cortical granule-plasma membrane attachment in the sea urchin egg" @default.
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- W2090898258 doi "https://doi.org/10.1016/0012-1606(81)90309-2" @default.
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