Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090900908> ?p ?o ?g. }
- W2090900908 abstract "Two new breast tumor cell lines (UISO-BC-1 and UISO-BC-2) have been established from pleural effusions obtained from patients with confirmed diagnosis of breast cancer. Cytogenetic investigation shows several numerical and structural aberrations in both cell lines. Each cell line appears to have distinctive karyotypic aberrations. Although a common marker chromosome was not found in both cell lines, several breakpoints (i.e., 1q11, 3q11, 7p11, 9q11, and 13q11) were commonly involved in the marker chromosomes of both lines. Double minute (dmin) chromosomes were also observed in these two cell lines. Sixteen oncogene probes were used to study the oncogene amplification and overexpression; among these, only neu and c-myc probes detected multiple gene copies. A 10-fold amplification and a 20-fold overexpression of the neu were observed in the UISO-BC-1 line, whereas a threefold and a fivefold amplification of c-myc were found in UISO-BC-1 and UISO-BC-2, respectively. Moderately enhanced expression (sixfold) of c-myc was also observed in the UISO-BS-2 line. No gross rearrangement of these genes or aberrant RNAs was detected in these tumor cell lines." @default.
- W2090900908 created "2016-06-24" @default.
- W2090900908 creator A5002476558 @default.
- W2090900908 creator A5004041048 @default.
- W2090900908 creator A5022527568 @default.
- W2090900908 creator A5043380622 @default.
- W2090900908 creator A5062063724 @default.
- W2090900908 creator A5078000811 @default.
- W2090900908 date "1991-02-01" @default.
- W2090900908 modified "2023-09-24" @default.
- W2090900908 title "Chromosome aberrations and oncogene alterations in two new breast tumor cell lines" @default.
- W2090900908 cites W1510473137 @default.
- W2090900908 cites W1580894495 @default.
- W2090900908 cites W1791604348 @default.
- W2090900908 cites W1807228574 @default.
- W2090900908 cites W187705992 @default.
- W2090900908 cites W189695663 @default.
- W2090900908 cites W1949052814 @default.
- W2090900908 cites W1983837188 @default.
- W2090900908 cites W1984746881 @default.
- W2090900908 cites W2001627828 @default.
- W2090900908 cites W2005764975 @default.
- W2090900908 cites W2010394574 @default.
- W2090900908 cites W2012666964 @default.
- W2090900908 cites W2013396526 @default.
- W2090900908 cites W2014669590 @default.
- W2090900908 cites W2017164036 @default.
- W2090900908 cites W2023640859 @default.
- W2090900908 cites W2024378792 @default.
- W2090900908 cites W2043660349 @default.
- W2090900908 cites W2048324748 @default.
- W2090900908 cites W2050688761 @default.
- W2090900908 cites W2055787036 @default.
- W2090900908 cites W2057301899 @default.
- W2090900908 cites W2057934537 @default.
- W2090900908 cites W2060333964 @default.
- W2090900908 cites W2060531515 @default.
- W2090900908 cites W2063450941 @default.
- W2090900908 cites W2063654777 @default.
- W2090900908 cites W2065929170 @default.
- W2090900908 cites W2075358739 @default.
- W2090900908 cites W2077077811 @default.
- W2090900908 cites W2078713539 @default.
- W2090900908 cites W2082777785 @default.
- W2090900908 cites W2088336419 @default.
- W2090900908 cites W2090545948 @default.
- W2090900908 cites W2092229345 @default.
- W2090900908 cites W2093189266 @default.
- W2090900908 cites W2095402260 @default.
- W2090900908 cites W2096203950 @default.
- W2090900908 cites W2106495814 @default.
- W2090900908 cites W2120178047 @default.
- W2090900908 cites W2125079668 @default.
- W2090900908 cites W2142800802 @default.
- W2090900908 cites W2147650665 @default.
- W2090900908 cites W2149535267 @default.
- W2090900908 cites W2160544249 @default.
- W2090900908 cites W2224929038 @default.
- W2090900908 cites W2266955236 @default.
- W2090900908 cites W2281315621 @default.
- W2090900908 cites W2406020694 @default.
- W2090900908 cites W2433878972 @default.
- W2090900908 cites W981450589 @default.
- W2090900908 doi "https://doi.org/10.1016/0165-4608(91)90137-j" @default.
- W2090900908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1704295" @default.
- W2090900908 hasPublicationYear "1991" @default.
- W2090900908 type Work @default.
- W2090900908 sameAs 2090900908 @default.
- W2090900908 citedByCount "9" @default.
- W2090900908 crossrefType "journal-article" @default.
- W2090900908 hasAuthorship W2090900908A5002476558 @default.
- W2090900908 hasAuthorship W2090900908A5004041048 @default.
- W2090900908 hasAuthorship W2090900908A5022527568 @default.
- W2090900908 hasAuthorship W2090900908A5043380622 @default.
- W2090900908 hasAuthorship W2090900908A5062063724 @default.
- W2090900908 hasAuthorship W2090900908A5078000811 @default.
- W2090900908 hasConcept C104317684 @default.
- W2090900908 hasConcept C130773972 @default.
- W2090900908 hasConcept C1491633281 @default.
- W2090900908 hasConcept C153911025 @default.
- W2090900908 hasConcept C206936463 @default.
- W2090900908 hasConcept C2781018059 @default.
- W2090900908 hasConcept C29537977 @default.
- W2090900908 hasConcept C30481170 @default.
- W2090900908 hasConcept C502942594 @default.
- W2090900908 hasConcept C53226629 @default.
- W2090900908 hasConcept C54355233 @default.
- W2090900908 hasConcept C67082663 @default.
- W2090900908 hasConcept C7602840 @default.
- W2090900908 hasConcept C81885089 @default.
- W2090900908 hasConcept C86803240 @default.
- W2090900908 hasConceptScore W2090900908C104317684 @default.
- W2090900908 hasConceptScore W2090900908C130773972 @default.
- W2090900908 hasConceptScore W2090900908C1491633281 @default.
- W2090900908 hasConceptScore W2090900908C153911025 @default.
- W2090900908 hasConceptScore W2090900908C206936463 @default.
- W2090900908 hasConceptScore W2090900908C2781018059 @default.
- W2090900908 hasConceptScore W2090900908C29537977 @default.
- W2090900908 hasConceptScore W2090900908C30481170 @default.
- W2090900908 hasConceptScore W2090900908C502942594 @default.