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• W2090903044 startingPage "72" @default.
• W2090903044 abstract "Individuals are frequently faced with risky decisions involving the potential for both gain and loss. Exploring the role of both potential gains and potential losses in predicting risk taking is critical to understanding how adolescents and adults make the choice to engage in or avoid a real-life risk. This study aimed to examine the impact of potential losses as well as gains on adolescent decisions during risky choice in a laboratory task. Adolescent (n=18) and adult (n=16) participants underwent functional magnetic resonance imaging (fMRI) during a mixed gambles task, and completed questionnaires measuring real-world risk-taking behaviors. While potential loss had a significantly greater effect on choice than potential gain in both adolescents and adults and there were no behavioral group differences on the task, adolescents recruited significantly more frontostriatal circuitry than adults when choosing to reject a gamble. During risk-seeking behavior, adolescent activation in medial prefrontal cortex (mPFC) was negatively correlated with self-reported likelihood of risk taking. During risk-avoidant behavior, mPFC activation of in adults was negatively correlated with self-reported benefits of risk-taking. Taken together, these findings reflect different neural patterns during risk-taking and risk-avoidant behaviors in adolescents and adults." @default.
• W2090903044 created "2016-06-24" @default.
• W2090903044 creator A5005906639 @default.
• W2090903044 creator A5050937985 @default.
• W2090903044 creator A5056482545 @default.
• W2090903044 date "2013-01-01" @default.
• W2090903044 modified "2023-10-12" @default.
• W2090903044 title "Behavioral and neural correlates of loss aversion and risk avoidance in adolescents and adults" @default.
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• W2090903044 doi "https://doi.org/10.1016/j.dcn.2012.09.007" @default.
• W2090903044 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6987718" @default.
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• W2090903044 hasPublicationYear "2013" @default.
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