FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090908310> ?p ?o ?g. }

• W2090908310 endingPage "189" @default.
• W2090908310 startingPage "187" @default.
• W2090908310 abstract "present in 97.5% 30 min after the procedure. Patient satisfaction was also very good with 99.8% willing to repeat the same procedure. These findings serve to further confirm the strong impression that propofol is safe for use as a conscious sedation agent for endoscopy in the hands of appropriately trained endoscopists and endoscopy nurses. There are several studies over the last few years (involving over 200,000 patients) examining propofol administration for endoscopy by gastroenterologists and specially trained endoscopy nurses [3–9] . A recent metaanalysis found no increase in the risk of cardio-pulmonary complications with the use of propofol sedation for endoscopy, as compared to the use of traditional sedative agents. There was not a single patient in these studies who required intubation or died. Nonetheless, despite the plethora of safety data relating to the use of propofol by endoscopists and endoscopy nurses, there are still concerns within the community. A key factor is appropriate patient selection as there is a more recent study which reported a very small number of deaths in patients who received propofol for conscious sedation, most of whom were undergoing more prolonged procedures and/or were higher risk ASA (American Society of Anesthesiologists) class [10] . Of note, none of the patients in this recent series underwent colonoscopy or standard routine gastroscopy. The current study by Horiuchi et al. [2] focuses on lowdose propofol in diagnostic EGD, and irrefutably confirms the safety of such a practice. Many of us are familiar with the situation in which a patient is somewhat combative during an endoscopic procedure, but sleeps like a baby for what seems an age afterwards. Despite undoubted advances in this area, it is glaringly obvious that we have significant room for improvement in how we sedate patients. So, what about propofol? Propofol is an intravenous anesthetic agent often used with other agents for delivery of general anesthesia, but increasingly used in lower doses to induce conscious sedation. Hardly a month goes by without some study supporting the use of propofol by non-anesthesiologists for conscious sedation. Propofol has some undoubted advantages over benzodiazepines and opiates [1] . A particular advantage that is much cited by advocates of using propofol for conscious sedation is that it has a very short half-life, between 2 and 4 min, so there is a much shorter time to recovery from the drug than with midazolam, which has a 30-minute half-life. Rapid induction of sedation and subsequent patient recovery would accelerate patient turnover, allowing more procedures to be done per session. Would this be achieved at the expense of safety? It would appear not. In this issue of Digestion , Horiuchi et al. [2] from Japan prospectively look at the safety of nurse-administered low-dose propofol (30–80 mg total) for diagnostic esophagogastroduodenoscopy (EGD). An impressive 12,031 patients were studied. Only 1.1% of subjects developed transient oxygen desaturation, and full recovery was Published online: December 18, 2008" @default.
• W2090908310 created "2016-06-24" @default.
• W2090908310 creator A5062196297 @default.
• W2090908310 date "2008-01-01" @default.
• W2090908310 modified "2023-09-25" @default.
• W2090908310 title "Nurse-Administered Propofol Sedation Safety Further Confirmed – but Can We Really Allow Our Patients to Drive Afterwards?" @default.
• W2090908310 cites W1978381685 @default.
• W2090908310 cites W1979694637 @default.
• W2090908310 cites W2000123949 @default.
• W2090908310 cites W2000751827 @default.
• W2090908310 cites W2029474012 @default.
• W2090908310 cites W2036900595 @default.
• W2090908310 cites W2089629858 @default.
• W2090908310 cites W2134806986 @default.
• W2090908310 cites W2149873887 @default.
• W2090908310 cites W2154639860 @default.
• W2090908310 cites W2520894846 @default.
• W2090908310 doi "https://doi.org/10.1159/000187117" @default.
• W2090908310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19092245" @default.
• W2090908310 hasPublicationYear "2008" @default.
• W2090908310 type Work @default.
• W2090908310 sameAs 2090908310 @default.
• W2090908310 citedByCount "1" @default.
• W2090908310 countsByYear W20909083102012 @default.
• W2090908310 crossrefType "journal-article" @default.
• W2090908310 hasAuthorship W2090908310A5062196297 @default.
• W2090908310 hasBestOaLocation W20909083101 @default.
• W2090908310 hasConcept C15744967 @default.
• W2090908310 hasConcept C159110408 @default.
• W2090908310 hasConcept C160735492 @default.
• W2090908310 hasConcept C162324750 @default.
• W2090908310 hasConcept C177713679 @default.
• W2090908310 hasConcept C2776277131 @default.
• W2090908310 hasConcept C2776814716 @default.
• W2090908310 hasConcept C2779328685 @default.
• W2090908310 hasConcept C42219234 @default.
• W2090908310 hasConcept C50522688 @default.
• W2090908310 hasConcept C545542383 @default.
• W2090908310 hasConcept C71924100 @default.
• W2090908310 hasConceptScore W2090908310C15744967 @default.
• W2090908310 hasConceptScore W2090908310C159110408 @default.
• W2090908310 hasConceptScore W2090908310C160735492 @default.
• W2090908310 hasConceptScore W2090908310C162324750 @default.
• W2090908310 hasConceptScore W2090908310C177713679 @default.
• W2090908310 hasConceptScore W2090908310C2776277131 @default.
• W2090908310 hasConceptScore W2090908310C2776814716 @default.
• W2090908310 hasConceptScore W2090908310C2779328685 @default.
• W2090908310 hasConceptScore W2090908310C42219234 @default.
• W2090908310 hasConceptScore W2090908310C50522688 @default.
• W2090908310 hasConceptScore W2090908310C545542383 @default.
• W2090908310 hasConceptScore W2090908310C71924100 @default.
• W2090908310 hasIssue "4" @default.
• W2090908310 hasLocation W20909083101 @default.
• W2090908310 hasLocation W20909083102 @default.
• W2090908310 hasOpenAccess W2090908310 @default.
• W2090908310 hasPrimaryLocation W20909083101 @default.
• W2090908310 hasRelatedWork W130425198 @default.
• W2090908310 hasRelatedWork W163357817 @default.
• W2090908310 hasRelatedWork W1967433557 @default.
• W2090908310 hasRelatedWork W1968054402 @default.
• W2090908310 hasRelatedWork W1985198936 @default.
• W2090908310 hasRelatedWork W2001683931 @default.
• W2090908310 hasRelatedWork W2360548818 @default.
• W2090908310 hasRelatedWork W2373888550 @default.
• W2090908310 hasRelatedWork W67055460 @default.
• W2090908310 hasRelatedWork W2184511288 @default.
• W2090908310 hasVolume "78" @default.
• W2090908310 isParatext "false" @default.
• W2090908310 isRetracted "false" @default.
• W2090908310 magId "2090908310" @default.
• W2090908310 workType "article" @default.