FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090909844> ?p ?o ?g. }

• W2090909844 endingPage "129" @default.
• W2090909844 startingPage "116" @default.
• W2090909844 abstract "Renal dendritic cells (DCs) form an interstitial network contributing to inflammatory and adaptive immune responses in the kidney. The presence and functional role of DC-like glomerular CD11c(+) mononuclear phagocytes is a matter of debate. Using compartment-specific flow cytometry we found that healthy mouse kidneys contained 1.3 CD11c(+) cells per 100 glomeruli and these increased by 4.6-fold and 13-fold after TNF stimulation and immune complex deposition, respectively. Compartment-specific mRNA expression revealed a predominantly glomerular expression of TNF receptors, chemokines, and adhesion molecules; all upregulated after TNF exposure. Intraperitoneal TNF injection induced influx of neutrophils and mononuclear phagocytes including DC-like CD11c(+) cells into both the glomerular and tubulointerstitial compartments, but reduced in TNF receptor (Tnfr) 1-deficient mice. Additionally, Tnfr2 deficiency impaired glomerular infiltration of CD11c(+) cells, but not neutrophils. Interstitial CD11c(+) cells infiltrated in the presence of Tnfr1 or Tnfr2. TNF exposure also induced similar maturation of glomerular and interstitial CD11c(+) cells as demonstrated by increased surface expression of MHC II, CD54, and costimulatory molecules CD40, CD80, and CD86. Thus, by compartment-specific flow cytometry we could demonstrate the constitutive presence of DC-like CD11c(+) mononuclear phagocytes in normal mouse glomeruli and their TNF-induced accumulation and activation." @default.
• W2090909844 created "2016-06-24" @default.
• W2090909844 creator A5004742967 @default.
• W2090909844 creator A5020103420 @default.
• W2090909844 creator A5053753989 @default.
• W2090909844 creator A5072125974 @default.
• W2090909844 creator A5087042524 @default.
• W2090909844 creator A5090067960 @default.
• W2090909844 date "2013-07-01" @default.
• W2090909844 modified "2023-10-12" @default.
• W2090909844 title "Analysis of TNF-mediated recruitment and activation of glomerular dendritic cells in mouse kidneys by compartment-specific flow cytometry" @default.
• W2090909844 cites W1661544713 @default.
• W2090909844 cites W1677024991 @default.
• W2090909844 cites W1964538893 @default.
• W2090909844 cites W1977298268 @default.
• W2090909844 cites W1979509921 @default.
• W2090909844 cites W1982143675 @default.
• W2090909844 cites W1984820938 @default.
• W2090909844 cites W1994133347 @default.
• W2090909844 cites W1996498079 @default.
• W2090909844 cites W1999755139 @default.
• W2090909844 cites W2003597229 @default.
• W2090909844 cites W2018509996 @default.
• W2090909844 cites W2023045132 @default.
• W2090909844 cites W2027044758 @default.
• W2090909844 cites W2039904924 @default.
• W2090909844 cites W2053180390 @default.
• W2090909844 cites W2063960165 @default.
• W2090909844 cites W2075061310 @default.
• W2090909844 cites W2075574522 @default.
• W2090909844 cites W2079676318 @default.
• W2090909844 cites W2081685243 @default.
• W2090909844 cites W2085594812 @default.
• W2090909844 cites W2088037820 @default.
• W2090909844 cites W2089737288 @default.
• W2090909844 cites W2091635516 @default.
• W2090909844 cites W2095337395 @default.
• W2090909844 cites W2101617710 @default.
• W2090909844 cites W2104636490 @default.
• W2090909844 cites W2110318152 @default.
• W2090909844 cites W2110358511 @default.
• W2090909844 cites W2111504178 @default.
• W2090909844 cites W2126177422 @default.
• W2090909844 cites W2132552157 @default.
• W2090909844 cites W2137054971 @default.
• W2090909844 cites W2138210036 @default.
• W2090909844 cites W2145381900 @default.
• W2090909844 cites W2148977472 @default.
• W2090909844 cites W2153750939 @default.
• W2090909844 cites W2168784022 @default.
• W2090909844 cites W2169638459 @default.
• W2090909844 cites W2171815100 @default.
• W2090909844 cites W2316030220 @default.
• W2090909844 cites W4247406457 @default.
• W2090909844 doi "https://doi.org/10.1038/ki.2013.46" @default.
• W2090909844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23466995" @default.
• W2090909844 hasPublicationYear "2013" @default.
• W2090909844 type Work @default.
• W2090909844 sameAs 2090909844 @default.
• W2090909844 citedByCount "24" @default.
• W2090909844 countsByYear W20909098442014 @default.
• W2090909844 countsByYear W20909098442015 @default.
• W2090909844 countsByYear W20909098442016 @default.
• W2090909844 countsByYear W20909098442017 @default.
• W2090909844 countsByYear W20909098442018 @default.
• W2090909844 countsByYear W20909098442019 @default.
• W2090909844 countsByYear W20909098442020 @default.
• W2090909844 countsByYear W20909098442021 @default.
• W2090909844 countsByYear W20909098442023 @default.
• W2090909844 crossrefType "journal-article" @default.
• W2090909844 hasAuthorship W2090909844A5004742967 @default.
• W2090909844 hasAuthorship W2090909844A5020103420 @default.
• W2090909844 hasAuthorship W2090909844A5053753989 @default.
• W2090909844 hasAuthorship W2090909844A5072125974 @default.
• W2090909844 hasAuthorship W2090909844A5087042524 @default.
• W2090909844 hasAuthorship W2090909844A5090067960 @default.
• W2090909844 hasBestOaLocation W20909098441 @default.
• W2090909844 hasConcept C104317684 @default.
• W2090909844 hasConcept C127716648 @default.
• W2090909844 hasConcept C13373296 @default.
• W2090909844 hasConcept C137061746 @default.
• W2090909844 hasConcept C154317977 @default.
• W2090909844 hasConcept C17991360 @default.
• W2090909844 hasConcept C185592680 @default.
• W2090909844 hasConcept C202751555 @default.
• W2090909844 hasConcept C203014093 @default.
• W2090909844 hasConcept C2776090121 @default.
• W2090909844 hasConcept C2778170410 @default.
• W2090909844 hasConcept C2778297628 @default.
• W2090909844 hasConcept C2779919695 @default.
• W2090909844 hasConcept C2781101188 @default.
• W2090909844 hasConcept C39347974 @default.
• W2090909844 hasConcept C553184892 @default.
• W2090909844 hasConcept C55493867 @default.
• W2090909844 hasConcept C86803240 @default.
• W2090909844 hasConcept C8891405 @default.
• W2090909844 hasConcept C95444343 @default.
• W2090909844 hasConceptScore W2090909844C104317684 @default.

• next