Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090920104> ?p ?o ?g. }
- W2090920104 endingPage "60" @default.
- W2090920104 startingPage "55" @default.
- W2090920104 abstract "Sensorimotor gating can be measured as prepulse inhibition of the startle response in humans and rats. Since prepulse inhibition is impaired in schizophrenics there is considerable interest in understanding the neuronal basis of prepulse inhibition. Neuropathological findings indicate a dysfunction of the glutamatergic and GABAergic system in cortico-limbic areas in schizophrenics. We tested whether blockade of N-methyl-D-aspartate or GABA(A) receptors in the basolateral amygdala affects prepulse inhibition in rats. Local infusion of the N-methyl-D-aspartate receptor antagonist dizocilpine (0, 6.25 microg/0.5 microl), or of the GABA(A) receptor antagonist picrotoxin (0, 5.0, 10.0 ng/0.5 microl) reduced prepulse inhibition. The prepulse inhibition-disrupting effect of 6.25 microg dizocilpine or 10.0 ng picrotoxin was reversed by systemic co-administration of the dopamine antagonist haloperidol (0.1mg/kg i.p.). These data indicate that sensorimotor gating is regulated in a dopamine-dependent way by N-methyl-D-aspartate and GABA(A) receptors in the basolateral amygdala. Our findings are discussed with respect to neuropathological findings in schizophrenics." @default.
- W2090920104 created "2016-06-24" @default.
- W2090920104 creator A5014887451 @default.
- W2090920104 creator A5043590088 @default.
- W2090920104 creator A5073496919 @default.
- W2090920104 date "2000-06-01" @default.
- W2090920104 modified "2023-10-14" @default.
- W2090920104 title "Amygdaloid N-methyl-d-aspartate and γ-aminobutyric acidA receptors regulate sensorimotor gating in a dopamine-dependent way in rats" @default.
- W2090920104 cites W144271823 @default.
- W2090920104 cites W1485031809 @default.
- W2090920104 cites W1633341882 @default.
- W2090920104 cites W1848820184 @default.
- W2090920104 cites W1966828597 @default.
- W2090920104 cites W1988790725 @default.
- W2090920104 cites W1990414759 @default.
- W2090920104 cites W1993855559 @default.
- W2090920104 cites W1995383486 @default.
- W2090920104 cites W2003289804 @default.
- W2090920104 cites W2003660243 @default.
- W2090920104 cites W2004928159 @default.
- W2090920104 cites W2005111389 @default.
- W2090920104 cites W2006954834 @default.
- W2090920104 cites W2008553208 @default.
- W2090920104 cites W2013032568 @default.
- W2090920104 cites W2017127193 @default.
- W2090920104 cites W2021099633 @default.
- W2090920104 cites W2024406994 @default.
- W2090920104 cites W2028337484 @default.
- W2090920104 cites W2029277771 @default.
- W2090920104 cites W2030247720 @default.
- W2090920104 cites W2030538289 @default.
- W2090920104 cites W2030626220 @default.
- W2090920104 cites W2042847262 @default.
- W2090920104 cites W2045505416 @default.
- W2090920104 cites W2052815900 @default.
- W2090920104 cites W2060441063 @default.
- W2090920104 cites W2066127633 @default.
- W2090920104 cites W2077679777 @default.
- W2090920104 cites W2078446073 @default.
- W2090920104 cites W2088366298 @default.
- W2090920104 cites W2096964020 @default.
- W2090920104 cites W2124389210 @default.
- W2090920104 cites W2133562098 @default.
- W2090920104 cites W2135731923 @default.
- W2090920104 cites W2140156016 @default.
- W2090920104 cites W2159648246 @default.
- W2090920104 cites W2168529228 @default.
- W2090920104 cites W4302309364 @default.
- W2090920104 doi "https://doi.org/10.1016/s0306-4522(00)00086-5" @default.
- W2090920104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10858611" @default.
- W2090920104 hasPublicationYear "2000" @default.
- W2090920104 type Work @default.
- W2090920104 sameAs 2090920104 @default.
- W2090920104 citedByCount "54" @default.
- W2090920104 countsByYear W20909201042012 @default.
- W2090920104 countsByYear W20909201042013 @default.
- W2090920104 countsByYear W20909201042014 @default.
- W2090920104 countsByYear W20909201042015 @default.
- W2090920104 countsByYear W20909201042016 @default.
- W2090920104 countsByYear W20909201042018 @default.
- W2090920104 countsByYear W20909201042020 @default.
- W2090920104 countsByYear W20909201042021 @default.
- W2090920104 countsByYear W20909201042023 @default.
- W2090920104 crossrefType "journal-article" @default.
- W2090920104 hasAuthorship W2090920104A5014887451 @default.
- W2090920104 hasAuthorship W2090920104A5043590088 @default.
- W2090920104 hasAuthorship W2090920104A5073496919 @default.
- W2090920104 hasConcept C118552586 @default.
- W2090920104 hasConcept C120069818 @default.
- W2090920104 hasConcept C126322002 @default.
- W2090920104 hasConcept C134018914 @default.
- W2090920104 hasConcept C141421786 @default.
- W2090920104 hasConcept C15744967 @default.
- W2090920104 hasConcept C169760540 @default.
- W2090920104 hasConcept C170493617 @default.
- W2090920104 hasConcept C185592680 @default.
- W2090920104 hasConcept C2776412080 @default.
- W2090920104 hasConcept C2776885963 @default.
- W2090920104 hasConcept C2777836312 @default.
- W2090920104 hasConcept C2779144063 @default.
- W2090920104 hasConcept C2779324764 @default.
- W2090920104 hasConcept C2780451725 @default.
- W2090920104 hasConcept C513476851 @default.
- W2090920104 hasConcept C67018056 @default.
- W2090920104 hasConcept C71924100 @default.
- W2090920104 hasConceptScore W2090920104C118552586 @default.
- W2090920104 hasConceptScore W2090920104C120069818 @default.
- W2090920104 hasConceptScore W2090920104C126322002 @default.
- W2090920104 hasConceptScore W2090920104C134018914 @default.
- W2090920104 hasConceptScore W2090920104C141421786 @default.
- W2090920104 hasConceptScore W2090920104C15744967 @default.
- W2090920104 hasConceptScore W2090920104C169760540 @default.
- W2090920104 hasConceptScore W2090920104C170493617 @default.
- W2090920104 hasConceptScore W2090920104C185592680 @default.
- W2090920104 hasConceptScore W2090920104C2776412080 @default.
- W2090920104 hasConceptScore W2090920104C2776885963 @default.
- W2090920104 hasConceptScore W2090920104C2777836312 @default.
- W2090920104 hasConceptScore W2090920104C2779144063 @default.