FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2090925401> ?p ?o ?g. }

• W2090925401 endingPage "3704" @default.
• W2090925401 startingPage "3700" @default.
• W2090925401 abstract "To investigate the function of base 792 of 16S rRNA in 30S ribosomes of Escherichia coli, the wild-type (adenine) residue was changed to guanine, cytosine, or uracil by oligonucleotide-directed mutagenesis. Each base change conferred a unique phenotype on the cells. Cells containing plasmid pKK3535 with G792 or T792 showed no difference in generation time in LB broth containing ampicillin, whereas cells with C792 exhibited a 20% increase in generation time in this medium. To study the effect on cell growth of a homogeneous population of mutant ribosomes, the mutations were cloned into the 16S rRNA gene on pKK3535 carrying a spectinomycin-resistance marker (thymine at position 1192), and the cells were grown with spectinomycin. Cells containing G792 or C792 showed 16% and 56% increases in generation time, respectively, and a concomitant decrease in 35S assimilation into proteins. Cells with T792 did not grow in spectinomycin-containing medium. Maxicell analyses indicated decreasing ability to form 70S ribosomes from 30S subunits containing guanine, cytosine, or uracil at position 792 in 16S rRNA. It appeared that C792-containing 30S ribosomes had lost the ability to bind initiation factor 3." @default.
• W2090925401 created "2016-06-24" @default.
• W2090925401 creator A5008733073 @default.
• W2090925401 creator A5015274110 @default.
• W2090925401 creator A5015524868 @default.
• W2090925401 creator A5024457596 @default.
• W2090925401 creator A5045013896 @default.
• W2090925401 creator A5046662577 @default.
• W2090925401 creator A5061041559 @default.
• W2090925401 creator A5061516239 @default.
• W2090925401 creator A5082273868 @default.
• W2090925401 creator A5088652167 @default.
• W2090925401 date "1990-05-01" @default.
• W2090925401 modified "2023-10-16" @default.
• W2090925401 title "Base changes at position 792 of Escherichia coli 16S rRNA affect assembly of 70S ribosomes." @default.
• W2090925401 cites W1516335958 @default.
• W2090925401 cites W1526839250 @default.
• W2090925401 cites W1536871692 @default.
• W2090925401 cites W1547205596 @default.
• W2090925401 cites W1564890115 @default.
• W2090925401 cites W1967977918 @default.
• W2090925401 cites W1973241521 @default.
• W2090925401 cites W1975993749 @default.
• W2090925401 cites W1976199676 @default.
• W2090925401 cites W1979758876 @default.
• W2090925401 cites W1986689971 @default.
• W2090925401 cites W1992595091 @default.
• W2090925401 cites W2001916877 @default.
• W2090925401 cites W2009222089 @default.
• W2090925401 cites W2010978910 @default.
• W2090925401 cites W2018289835 @default.
• W2090925401 cites W2026358434 @default.
• W2090925401 cites W2033047771 @default.
• W2090925401 cites W2036931150 @default.
• W2090925401 cites W2041815688 @default.
• W2090925401 cites W2045880439 @default.
• W2090925401 cites W2079014695 @default.
• W2090925401 cites W2083350289 @default.
• W2090925401 cites W2085905473 @default.
• W2090925401 cites W2100837269 @default.
• W2090925401 cites W2114039447 @default.
• W2090925401 cites W2138270253 @default.
• W2090925401 cites W2157010941 @default.
• W2090925401 cites W2280290540 @default.
• W2090925401 cites W2888511473 @default.
• W2090925401 doi "https://doi.org/10.1073/pnas.87.10.3700" @default.
• W2090925401 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/53970" @default.
• W2090925401 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2140191" @default.
• W2090925401 hasPublicationYear "1990" @default.
• W2090925401 type Work @default.
• W2090925401 sameAs 2090925401 @default.
• W2090925401 citedByCount "28" @default.
• W2090925401 countsByYear W20909254012017 @default.
• W2090925401 crossrefType "journal-article" @default.
• W2090925401 hasAuthorship W2090925401A5008733073 @default.
• W2090925401 hasAuthorship W2090925401A5015274110 @default.
• W2090925401 hasAuthorship W2090925401A5015524868 @default.
• W2090925401 hasAuthorship W2090925401A5024457596 @default.
• W2090925401 hasAuthorship W2090925401A5045013896 @default.
• W2090925401 hasAuthorship W2090925401A5046662577 @default.
• W2090925401 hasAuthorship W2090925401A5061041559 @default.
• W2090925401 hasAuthorship W2090925401A5061516239 @default.
• W2090925401 hasAuthorship W2090925401A5082273868 @default.
• W2090925401 hasAuthorship W2090925401A5088652167 @default.
• W2090925401 hasBestOaLocation W20909254011 @default.
• W2090925401 hasConcept C104317684 @default.
• W2090925401 hasConcept C153911025 @default.
• W2090925401 hasConcept C2776023528 @default.
• W2090925401 hasConcept C2776858809 @default.
• W2090925401 hasConcept C2778063948 @default.
• W2090925401 hasConcept C2778301229 @default.
• W2090925401 hasConcept C2779554091 @default.
• W2090925401 hasConcept C2780923616 @default.
• W2090925401 hasConcept C501593827 @default.
• W2090925401 hasConcept C512185932 @default.
• W2090925401 hasConcept C547475151 @default.
• W2090925401 hasConcept C552990157 @default.
• W2090925401 hasConcept C55493867 @default.
• W2090925401 hasConcept C67705224 @default.
• W2090925401 hasConcept C67905577 @default.
• W2090925401 hasConcept C86803240 @default.
• W2090925401 hasConcept C88478588 @default.
• W2090925401 hasConceptScore W2090925401C104317684 @default.
• W2090925401 hasConceptScore W2090925401C153911025 @default.
• W2090925401 hasConceptScore W2090925401C2776023528 @default.
• W2090925401 hasConceptScore W2090925401C2776858809 @default.
• W2090925401 hasConceptScore W2090925401C2778063948 @default.
• W2090925401 hasConceptScore W2090925401C2778301229 @default.
• W2090925401 hasConceptScore W2090925401C2779554091 @default.
• W2090925401 hasConceptScore W2090925401C2780923616 @default.
• W2090925401 hasConceptScore W2090925401C501593827 @default.
• W2090925401 hasConceptScore W2090925401C512185932 @default.
• W2090925401 hasConceptScore W2090925401C547475151 @default.
• W2090925401 hasConceptScore W2090925401C552990157 @default.
• W2090925401 hasConceptScore W2090925401C55493867 @default.
• W2090925401 hasConceptScore W2090925401C67705224 @default.
• W2090925401 hasConceptScore W2090925401C67905577 @default.
• W2090925401 hasConceptScore W2090925401C86803240 @default.

• next