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- W2090971219 abstract "The effect of cyclosporin A (CSA) on the elicitation phase of allergic contact dermatitis was investigated. Initially, the ability of CSA to penetrate normal human cadaver skin was determined using 3 different vehicles. 10% CSA in Labrafil was found to be the must effective combination at achieving skin penetration (0.33%). Patients with known contact sensitivities to a variety of allergens were selected. After a 48-h pretreatment with 10% CSA in Labrafil, skin sites were exposed to the appropriate contact allergen. 72 h later, the development of an eczemutous patch test reaction was evaluated. Only 1 of 10 patients showed unequivocal signs of suppression of allergic contact dermatitis" @default.
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- W2090971219 date "1988-08-01" @default.
- W2090971219 modified "2023-09-24" @default.
- W2090971219 title "The effect of topical cyclosporin A on the elicitation phase of allergic contact dermatitis" @default.
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- W2090971219 doi "https://doi.org/10.1111/j.1600-0536.1988.tb05510.x" @default.
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