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- W2090972150 abstract "The improvement of electrochemical detection of meloxicam is presented bymodification of a glassy carbon electrode with anionic layer of cysteic acid providingelectrostatic accumulation of the analyte onto the electrode surface. The modificationformed by electrochemical oxidation of L-cysteine was performed by cycling potential incysteine solution. The anodic peak current obtained at 1.088 V (vs. Ag/AgCl) byvoltammetry was linearly dependent on the meloxicam concentration in the range of 4.3 ×10-8 ~ 8.5 × 10-6 M in the B-R buffer solution (0.04 M, pH 1.86) with a correlationcoefficient of 0.999. The detection limit (S/N = 3) is 1.5 × 10-9 M. The low-cost modifiedelectrode shows good sensitivity, selectivity and stability and has been applied to thedetermination of meloxicam in pharmaceutical formulation and spiked serum withsatisfactory results. The electrochemical reaction mechanism of meloxicam was discussed." @default.
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- W2090972150 date "2006-09-27" @default.
- W2090972150 modified "2023-09-27" @default.
- W2090972150 title "Voltammetric Determination of Meloxicam in Pharmaceutical Formulation and Human Serum at Glassy Carbon Electrode Modified by Cysteic Acid Formed by Electrochemical Oxidation of L-cysteine" @default.
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- W2090972150 doi "https://doi.org/10.3390/s6091139" @default.
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