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• W2090985888 abstract "The normal levels of Na, K and Cl in fresh bovine corneas were found to be close to those previously reported for rabbit corneas. The influx kinetics of these ions were studied by tracer techniques and it was found that, while over 90% of the sodium and chloride exchanged within 45 min, only 25% of potassium exchanged in that time. Ouabain drastically reduced potassium influx while it had little effect on the kinetics of Na and Cl. With the Ringer's solution developed for this study, minimal changes of hydration and ion balance occurred over the experimental period of 180 min. The effects of three classes of detergents on electrical resistance and ion movements in bovine cornea were studied. The order of effectiveness in reducing resistance, increasing the rate of potassium exchange and increasing hydration was cetyltrimethylammonium bromide > sodium dodecylsulphate > Triton X-100. The anionic detergent also caused a significant fall in the chloride content of the cornea. The data are discussed in terms of current epithelial and endothelial based models for the maintenance of normal corneal hydration." @default.
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• W2090985888 date "1973-12-01" @default.
• W2090985888 modified "2023-09-26" @default.
• W2090985888 title "Effects of detergents on the ionic balance and permeability of isolated bovine cornea" @default.
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• W2090985888 doi "https://doi.org/10.1016/0014-4835(73)90220-0" @default.
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