FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091051049> ?p ?o ?g. }

• W2091051049 endingPage "54" @default.
• W2091051049 startingPage "40" @default.
• W2091051049 abstract "Lymphocytes from apparently healthy subjects, incubated for 5 hours with cellular components or extracellular products of group A streptococci and then washed and reincubated, were found to release factor(s) capable of inhibiting guinea pig lung macrophage migration (“indirect method”). Inhibitition of macrophage migration was also obtained when the same preparations were tested directly on guinea pig lung cells, a macrophage-lymphocyte population (“direct method”). The guinea pigs had not been experimentally sensitized. The inhibition of migration appeared to depend on the presence of lymphocytes among the macrophages, since macrophages purified by repeatedly discarding nonadherent cells proved resistant to the migration inhibiting activity of the most active Streptococcal preparation, a 20 × concentrated filtrate. Reconstitution of the original lymphocyte-macrophage mixture reestablished the reactivity. The macrophage migration inhibition did not correlate with the age of the guinea pigs. It could not be obtained with preparations of group D streptococci or of Salmonella paratyphi. Group C streptococci did not inhibit the macrophage migration with the indirect method, but it did with the direct one. The factor(s) released into the medium on stimulation of apparently normal lymphocytes by Streptococcal preparations was relatively heat resistant, nondialyzable, and DNase and RNase resistant; its release was inhibited by puromycin. Pretreatment of the cells with trypsin prevented the absorption of the factor(s) and left migration unaffected. These characteristics are similar to those previously described for the migration inhibitory factor (MIF) produced by the interaction of sensitized lymphocytes and specific antigens. Whether or not these similarities indicate an identity remains to be determined." @default.
• W2091051049 created "2016-06-24" @default.
• W2091051049 creator A5052143029 @default.
• W2091051049 creator A5063546714 @default.
• W2091051049 date "1973-07-01" @default.
• W2091051049 modified "2023-10-16" @default.
• W2091051049 title "Release of macrophage migration inhibitory factor(s) from lymphocytes stimulated by streptococcal preparations" @default.
• W2091051049 cites W1502681603 @default.
• W2091051049 cites W1507607743 @default.
• W2091051049 cites W1510172189 @default.
• W2091051049 cites W1529488198 @default.
• W2091051049 cites W1775749144 @default.
• W2091051049 cites W1863622552 @default.
• W2091051049 cites W1946965837 @default.
• W2091051049 cites W1972459768 @default.
• W2091051049 cites W1999883872 @default.
• W2091051049 cites W2001634895 @default.
• W2091051049 cites W2011169411 @default.
• W2091051049 cites W2015581041 @default.
• W2091051049 cites W2033298594 @default.
• W2091051049 cites W2036283164 @default.
• W2091051049 cites W2039851243 @default.
• W2091051049 cites W2060686467 @default.
• W2091051049 cites W2066389545 @default.
• W2091051049 cites W2069326649 @default.
• W2091051049 cites W2074202544 @default.
• W2091051049 cites W2087533578 @default.
• W2091051049 cites W2132634609 @default.
• W2091051049 cites W2134776294 @default.
• W2091051049 cites W2143147342 @default.
• W2091051049 doi "https://doi.org/10.1016/0008-8749(73)90091-9" @default.
• W2091051049 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4738315" @default.
• W2091051049 hasPublicationYear "1973" @default.
• W2091051049 type Work @default.
• W2091051049 sameAs 2091051049 @default.
• W2091051049 citedByCount "13" @default.
• W2091051049 crossrefType "journal-article" @default.
• W2091051049 hasAuthorship W2091051049A5052143029 @default.
• W2091051049 hasAuthorship W2091051049A5063546714 @default.
• W2091051049 hasConcept C104177226 @default.
• W2091051049 hasConcept C134018914 @default.
• W2091051049 hasConcept C147483822 @default.
• W2091051049 hasConcept C153911025 @default.
• W2091051049 hasConcept C181199279 @default.
• W2091051049 hasConcept C202751555 @default.
• W2091051049 hasConcept C203014093 @default.
• W2091051049 hasConcept C2777761686 @default.
• W2091051049 hasConcept C2778690821 @default.
• W2091051049 hasConcept C2778815084 @default.
• W2091051049 hasConcept C2779200571 @default.
• W2091051049 hasConcept C2779244956 @default.
• W2091051049 hasConcept C2780340462 @default.
• W2091051049 hasConcept C28406088 @default.
• W2091051049 hasConcept C2908647359 @default.
• W2091051049 hasConcept C3675279 @default.
• W2091051049 hasConcept C55493867 @default.
• W2091051049 hasConcept C71924100 @default.
• W2091051049 hasConcept C86803240 @default.
• W2091051049 hasConcept C89423630 @default.
• W2091051049 hasConcept C99454951 @default.
• W2091051049 hasConceptScore W2091051049C104177226 @default.
• W2091051049 hasConceptScore W2091051049C134018914 @default.
• W2091051049 hasConceptScore W2091051049C147483822 @default.
• W2091051049 hasConceptScore W2091051049C153911025 @default.
• W2091051049 hasConceptScore W2091051049C181199279 @default.
• W2091051049 hasConceptScore W2091051049C202751555 @default.
• W2091051049 hasConceptScore W2091051049C203014093 @default.
• W2091051049 hasConceptScore W2091051049C2777761686 @default.
• W2091051049 hasConceptScore W2091051049C2778690821 @default.
• W2091051049 hasConceptScore W2091051049C2778815084 @default.
• W2091051049 hasConceptScore W2091051049C2779200571 @default.
• W2091051049 hasConceptScore W2091051049C2779244956 @default.
• W2091051049 hasConceptScore W2091051049C2780340462 @default.
• W2091051049 hasConceptScore W2091051049C28406088 @default.
• W2091051049 hasConceptScore W2091051049C2908647359 @default.
• W2091051049 hasConceptScore W2091051049C3675279 @default.
• W2091051049 hasConceptScore W2091051049C55493867 @default.
• W2091051049 hasConceptScore W2091051049C71924100 @default.
• W2091051049 hasConceptScore W2091051049C86803240 @default.
• W2091051049 hasConceptScore W2091051049C89423630 @default.
• W2091051049 hasConceptScore W2091051049C99454951 @default.
• W2091051049 hasIssue "1" @default.
• W2091051049 hasLocation W20910510491 @default.
• W2091051049 hasLocation W20910510492 @default.
• W2091051049 hasOpenAccess W2091051049 @default.
• W2091051049 hasPrimaryLocation W20910510491 @default.
• W2091051049 hasRelatedWork W1514149690 @default.
• W2091051049 hasRelatedWork W1570319510 @default.
• W2091051049 hasRelatedWork W1992489908 @default.
• W2091051049 hasRelatedWork W2002054157 @default.
• W2091051049 hasRelatedWork W2080603816 @default.
• W2091051049 hasRelatedWork W2091051049 @default.
• W2091051049 hasRelatedWork W2109351968 @default.
• W2091051049 hasRelatedWork W2417789235 @default.
• W2091051049 hasRelatedWork W2417792008 @default.
• W2091051049 hasRelatedWork W4313307363 @default.
• W2091051049 hasVolume "8" @default.
• W2091051049 isParatext "false" @default.

• next