FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2091054587> ?p ?o ?g. }

• W2091054587 endingPage "87" @default.
• W2091054587 startingPage "71" @default.
• W2091054587 abstract "Ibotenic acid lesions of the vertical limb of the diagonal band of Broca (VDB) in marmosets produced significant depletions in choline acetyltransferase (ChAT) activity and a decrease in acetylcholinesterase (AChE) staining in the hippocampal formation and entorhinal cortex (to which the cholinergic neurones of the VDB project) but not in the neocortex or amygdala. Marmosets with VDB lesions were impaired on acquisition (but not retention) of repeated trial visuospatial tasks. This impairment was amerliorated by pretreatment with the cholinergic agonist pilocarpine indicating (a) that the learning impairment was a consequence of damage to the cholinergic system and (b) that the cholinergic projections exert a modulatory or enabling function on the target areas which can be substituted by a non-impulse-dependent drug action. Unlike marmosets with lesions of the basal nucleus of Meynert (NBM), VDB-lesioned animals were not impaired on learning repeated trial object discrimination and showed no change in general behavior although they did become hypothermic and mesomorphic. These results are consistent with the suggestion that the hippocampus (perhaps in conjunction with the entorhinal cortex) is concerned primarily with memory for responses but not memory for reward and that lesions of the cholinergic system produce impairments equivalent to the effects of ablation of the terminal areas." @default.
• W2091054587 created "2016-06-24" @default.
• W2091054587 creator A5056786962 @default.
• W2091054587 creator A5070866281 @default.
• W2091054587 creator A5085787643 @default.
• W2091054587 creator A5088669682 @default.
• W2091054587 date "1988-07-01" @default.
• W2091054587 modified "2023-10-16" @default.
• W2091054587 title "Visuospatial learning impairment following lesion of the cholinergic projection to the hippocampus" @default.
• W2091054587 cites W1543972392 @default.
• W2091054587 cites W1968886958 @default.
• W2091054587 cites W1969735301 @default.
• W2091054587 cites W1970069940 @default.
• W2091054587 cites W1970694609 @default.
• W2091054587 cites W1971794055 @default.
• W2091054587 cites W1977600929 @default.
• W2091054587 cites W1980137851 @default.
• W2091054587 cites W1981025816 @default.
• W2091054587 cites W1984491391 @default.
• W2091054587 cites W1989456510 @default.
• W2091054587 cites W1989632439 @default.
• W2091054587 cites W2002083376 @default.
• W2091054587 cites W2003400004 @default.
• W2091054587 cites W2004713321 @default.
• W2091054587 cites W2007466093 @default.
• W2091054587 cites W2010120109 @default.
• W2091054587 cites W2011133476 @default.
• W2091054587 cites W2013854477 @default.
• W2091054587 cites W2015763756 @default.
• W2091054587 cites W2016254753 @default.
• W2091054587 cites W2016915418 @default.
• W2091054587 cites W2017169966 @default.
• W2091054587 cites W2024955074 @default.
• W2091054587 cites W2025543844 @default.
• W2091054587 cites W2028848902 @default.
• W2091054587 cites W2033319161 @default.
• W2091054587 cites W2034046047 @default.
• W2091054587 cites W2037047980 @default.
• W2091054587 cites W2037196565 @default.
• W2091054587 cites W2037338304 @default.
• W2091054587 cites W2037511788 @default.
• W2091054587 cites W2037651109 @default.
• W2091054587 cites W2038334877 @default.
• W2091054587 cites W2047057727 @default.
• W2091054587 cites W2047260578 @default.
• W2091054587 cites W2049111961 @default.
• W2091054587 cites W2049357954 @default.
• W2091054587 cites W2049502793 @default.
• W2091054587 cites W2052779118 @default.
• W2091054587 cites W2053116984 @default.
• W2091054587 cites W2062837885 @default.
• W2091054587 cites W2064896771 @default.
• W2091054587 cites W2068440136 @default.
• W2091054587 cites W2069502929 @default.
• W2091054587 cites W2072428599 @default.
• W2091054587 cites W2074263699 @default.
• W2091054587 cites W2076358196 @default.
• W2091054587 cites W2079490962 @default.
• W2091054587 cites W2080282080 @default.
• W2091054587 cites W2089489620 @default.
• W2091054587 cites W2091582768 @default.
• W2091054587 cites W2092082847 @default.
• W2091054587 cites W2093374391 @default.
• W2091054587 cites W2093613378 @default.
• W2091054587 cites W2095873344 @default.
• W2091054587 cites W2110765139 @default.
• W2091054587 cites W2112592443 @default.
• W2091054587 cites W2133320138 @default.
• W2091054587 cites W2134941195 @default.
• W2091054587 cites W2249257064 @default.
• W2091054587 doi "https://doi.org/10.1016/0006-8993(88)90348-4" @default.
• W2091054587 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3136860" @default.
• W2091054587 hasPublicationYear "1988" @default.
• W2091054587 type Work @default.
• W2091054587 sameAs 2091054587 @default.
• W2091054587 citedByCount "58" @default.
• W2091054587 countsByYear W20910545872012 @default.
• W2091054587 countsByYear W20910545872013 @default.
• W2091054587 countsByYear W20910545872017 @default.
• W2091054587 countsByYear W20910545872019 @default.
• W2091054587 countsByYear W20910545872023 @default.
• W2091054587 crossrefType "journal-article" @default.
• W2091054587 hasAuthorship W2091054587A5056786962 @default.
• W2091054587 hasAuthorship W2091054587A5070866281 @default.
• W2091054587 hasAuthorship W2091054587A5085787643 @default.
• W2091054587 hasAuthorship W2091054587A5088669682 @default.
• W2091054587 hasConcept C104966671 @default.
• W2091054587 hasConcept C148762608 @default.
• W2091054587 hasConcept C15744967 @default.
• W2091054587 hasConcept C169760540 @default.
• W2091054587 hasConcept C198399640 @default.
• W2091054587 hasConcept C22885893 @default.
• W2091054587 hasConcept C2776287375 @default.
• W2091054587 hasConcept C2776818558 @default.
• W2091054587 hasConcept C2777222312 @default.
• W2091054587 hasConcept C2777681179 @default.
• W2091054587 hasConcept C2778205193 @default.
• W2091054587 hasConcept C2780715579 @default.

• next